› 1a76

X-ray diffraction
2Å resolution

FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII

Released:
DOI: 10.2210/pdb1a76/pdb
PDB entry 1a76 coloured by chain, front view.
PDB entry 1a76 coloured by chain, side view.
PDB entry 1a76 coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.
Hwang KY, Baek K, Kim HY, Cho Y
Nat Struct Biol 5 707-13 (1998)
PMID: 9699635

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176698 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Flap endonuclease 1 Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 37.59 KDa
Source organism: Methanocaldococcus jannaschii
UniProt:
  • Canonical: Q58839 (Residues: 1-326; Coverage: 100%)
Gene names: MJ1444, fen
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MN 2 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 58.78Å b: 42.8Å c: 62.64Å
α: 90° β: 92.26° γ: 90°
R-values:
R R work R free
0.214 0.214 0.279

Quick links

Citations

20 review citations

Nucleases: diversity of structure, function and mechanism.
Yang W. (2011)
19 more

8 mentions without citation

Structural basis for recruitment of human flap endonuclease 1 to PCNA.
Sakurai et al. (2005)
7 more