Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Serine protease/helicase NS3 (preferred)
PDBe Complex ID:
PDB-CPX-150808 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease/helicase NS3
Molecule details ›
Chains: A, B, C
Length: 189 amino acids
Theoretical weight: 19.89 KDa
Source organism: Hepacivirus hominis
Expression system: Escherichia coli
UniProt:
Length: 189 amino acids
Theoretical weight: 19.89 KDa
Source organism: Hepacivirus hominis
Expression system: Escherichia coli
UniProt:
- Canonical:
P26663 (Residues: 1027-1215; Coverage: 6%)
