› 186d

Solution NMR

SOLUTION STRUCTURE OF THE TETRAHYMENA TELOMERIC REPEAT D(T2G4)4 G-TETRAPLEX

Released:
DOI: 10.2210/pdb186d/pdb
PDB entry 186d coloured by chain, ensemble of 7 models, front view.
PDB entry 186d coloured by chain, ensemble of 7 models, side view.
PDB entry 186d coloured by chain, ensemble of 7 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex.
Wang Y, Patel DJ
Structure 2 1141-56 (1994)
PMID: 7704525

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113364 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 24 nucleotides
Theoretical weight: 7.66 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

21 review citations

Quadruplex DNA: sequence, topology and structure.
Burge et al. (2006)
20 more

11 mentions without citation

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Patel et al. (2007)
10 more