2-pyrrolidone-5-carboxylic acid (Gln)

^ http://purl.obolibrary.org/obo/MOD_00040

A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid. [ DeltaMass:123 RESID:AA0031#GLN PubMed:1836357 http://www.unimod.org/modifications_view.php?editid1=28#Q OMSSA:110 ChEBI:30652 PubMed:26343 PubMed:3473473 PubMed:10214721 ]

Synonyms: MOD_RES Pyrrolidone carboxylic acid, 5-oxopyrrolidine-2-carboxylic acid, Pyroglutamyl, N-pyrrolidone carboxyl (N terminus), 5-oxoproline, 2-oxopyrrolidine-5-carboxylic acid, (2S)-5-oxo-2-pyrrolidinecarboxylic acid, PCA, ntermpeppyroq, Pyroglutamic Acid formed from Gln, pyroglutamic acid, PyrGlu(Gln), 2-pyrrolidone-5-carboxylic acid, 5-pyrrolidone-2-carboxylic acid

Term info

database cross reference
  • Origin: (Q)
  • MassAvg: (112.11)
  • DiffFormula: (C 0 H -3 N -1 O 0)
  • TermSpec: (N-term)
  • DiffMono: (-17.026549)
  • Source: (natural)
  • Formula: (C 5 H 6 N 1 O 2)
  • MassMono: (112.039853)
  • DiffAvg: (-17.03)
Alternate name from RESID
2-oxopyrrolidine-5-carboxylic acid

Label from MS DeltaMass
Pyroglutamic Acid formed from Gln

Alternate name from RESID
5-pyrrolidone-2-carboxylic acid

Short label from OMSSA

Label from MS DeltaMass
N-pyrrolidone carboxyl (N terminus)

Alternate name from RESID
pyroglutamic acid

Protein feature description from UniProtKB
MOD_RES Pyrrolidone carboxylic acid

Systematic name from RESID
(2S)-5-oxo-2-pyrrolidinecarboxylic acid

Alternate name from RESID
5-oxopyrrolidine-2-carboxylic acid

Name from RESID
2-pyrrolidone-5-carboxylic acid


DeltaMass gives a formula C 5 H 5 N 1 O 2 with mass 111.1

has related synonym

Gln->pyro-Glu, Pyro-glu from Q