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substitution analysis

^ http://purl.obolibrary.org/obo/MI_0810


In this approach, once a molecule is demonstrated to participate in an interaction, several substitution mutants are produced and tested in the binding assay to identify the residues which identity is crucial for the interaction. [ http://www.ncbi.nlm.nih.gov/pubmed/14755292 ]

Synonyms: substitut analysis

Term info

id

MI:0810

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