| MSD |
CAPRI:
Critical Assessment of PRediction of Interactions |
Round 4 of CAPRI community wide experiment on the comparative
evaluation of protein-protein docking for structure
prediction
Hosted By EMBL/EBI-MSD Group
Targets
Please use these files for standard
chain Identifiers
PLEASE NOTE: For submissions only files uploaded that conform
to the format defined in the starting files and described
in the format document will be
accepted as valid submissions. The submission procedure will
automatically reject files that fail format checking.
Target 10: Trimeric form of the TBEV envelope protein
From: Felix Rey and Stephane Bressanelli (LVMS-CNRS, Gif-sur-Yvette, France)
The envelope protein (entry 1SVB_A), which is a dimer at the surface of
the tick-borne encephalitis virus (TBEV) particle, becomes a trimer at
acid pH.
This conformational change induces membrane fusion during cell infection.
Docking may assume three-fold symmetry in the trimer, and ignore the
C-terminal domain of the protein, which moves substantially during the
transition.
Note: the models should have three chains labeled A, B and C.
Download
CAPRI4-10 (Deadline for submissions - Oct 12th midnight UK time)
Target 11: Cellulosome cohesin-dockerin complex (unbound-homology model)
From:
Maria J. Romao and Ana Luisa Carvalho (New University of Lisbon)
José A.M. Prates, Luís M.A. Ferreira and Carlos M.G.A. Fontes (Technical
University of Lisbon)
Cohesin is PDB entry 1ANU; dockerin is a homolog of entry 1DAQ, a NMR
structure.
Below, its sequence of 56 residues is shown aligned on that of 1DAQ for
homology modeling (50% identity).
------GDVNGDGTINSTDLTMLKRSVLR-AITLTDDAKARADVDKNGSINSTDVLLLSRYLL 56
1DAQ MSTKLYGDVNDDGKVNSTDAVALKRYVLRSGISINTDN---ADLNEDGRVNSTDLGILKRYIL
****.**.:**** . *** *** .*::. **::::* :****: :*.**:*
The same complex also appears as unbound/bound in Target 12. As
coordinates for the bound dockerin moiety of this target will be
communicated on Sept. 22, the deadline of submissions for Target 11
predictions has to be set to SEPT. 21 midnight (London time).
Download
CAPRI4-11 (CLOSED)
Target 12: Cellulosome cohesin-dockerin complex (unbound/bound)
From:
Maria J. Romao and Ana Luisa Carvalho (New University of Lisbon)
José A.M. Prates, Luís M.A. Ferreira and Carlos M.G.A. Fontes (Technical
University of Lisbon)
Cohesin is PDB entry 1ANU; dockerin is taken from the complex.
Coordinates for this target will be communicated on Sept. 22, with Oct. 12th
midnight as a deadline for submissions.
Download
CAPRI4-12 (Deadline for submissions - Oct 12th midnight UK time)
Target 13: SAG1-antibody complex (unbound/bound)
From:
Marc Graille & Frederic Ducancel (CEA Saclay, France)
SAG1 (entry 1KZQ subunit A) is a surface protein antigen of the
toxoplasmosis parasite. The Fab moiety is from the complex.
Download
CAPRI4-13 (Deadline for submissions - Oct 12th midnight UK time)
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