› 1onu

Solution NMR

NMDA RECEPTOR ANTAGONIST, CONANTOKIN-G, NMR, 17 STRUCTURES

Released:
DOI: 10.2210/pdb1onu/pdb
PDB entry 1onu coloured by chain, ensemble of 17 models, front view.
PDB entry 1onu coloured by chain, ensemble of 17 models, side view.
PDB entry 1onu coloured by chain, ensemble of 17 models, top view.
Source organism: Conus geographus
Primary publication:
Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
Skjaerbaek N, Nielsen KJ, Lewis RJ, Alewood P, Craik DJ
J Biol Chem 272 2291-9 (1997)
PMID: 8999936

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139440 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Conantokin-G Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.27 KDa
Source organism: Conus geographus
Expression system: Not provided
UniProt:
  • Canonical: P07231 (Residues: 81-97; Coverage: 22%)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CGU 5 x CGU

Experiments and Validation Details

Entry percentile scores
Refinement method: MOLECULAR DYNAMICS, SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

12 review citations

Conus venoms: a rich source of novel ion channel-targeted peptides.
Terlau et al. (2004)
11 more

5 mentions without citation

Discovery, synthesis, and structure-activity relationships of conotoxins.
Akondi et al. (2014)
4 more