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AXIN2 Homo sapiens
AXIN2 is differentially expressed in 49 experiments [69 up/68 dn]: 18 organism parts: cerebellum [1 up/0 dn], white blood cells [0 up/1 dn], ...; 17 disease states: normal [5 up/2 dn], glioblastoma [0 up/2 dn], ...; 14 cell types, 19 cell lines, 12 compound treatments and 11 other conditions.
Synonyms AXIN2, DKFZp781B0869
Orthologs axin2 (Danio rerio)  Axin2 (Mus musculus)  AXN2_RAT (Rattus norvegicus)  (Compare orthologs)
InterPro Term Axin beta-catenin binding, DIX, Regulator of G protein signalling, Regulator of G protein signalling superfamily
Diseases Colorectal cancer, Oligodontia-colorectal cancer syndrome
GO Terms Wnt receptor signaling pathway, beta-catenin binding, cell death, intracellular, negative regulation of Wnt receptor signaling pathway
Uniprot Q5H9R8  Q9BRF5  Q9Y2T1 
Search EB-eye ENSG00000168646
REST API
Expression Summary
117 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
2
5
Stromal cell Cell type
1
2
FLAP Compound treatment
2
MK886 Compound treatment
2
HNRPA2B Compound treatment
2
Not applicable Histology
2
Cystic change Histology
2
Glioblastoma Disease state
2
HeLa Cell line
2
Epithelial cell Cell type
2
Invasive ductal carcinoma Histology
1
1
Breast carcinoma Disease state
1
1
Normal Histology
2
N/a Test result
1
1
Cerebellum Organism part
1
MCF-7 Cell line
1
AGS Cell line
1
White blood cells Organism part
1
Caudate nucleus Organism part
1
Cigarette smoke Growth condition
1
Incubator control Growth condition
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
10 ng/ml LPS in media Growth condition
1
Frontal cortex, superior motor... Organism part
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
PC3 Cell line
1
Metastatic Disease staging
1
Media only Growth condition
1
Vascular smooth muscle cell Cell type
1
Beas2B Cell line
1
Spermatid Cell type
1
YCC3 Cell line
1
Lymphatic endothelial cell Cell type
1
Cigarette smoke Compound treatment
1
MDA-MB-231 Cell line
1
Grade IV Tumor grading
1
Johnsen score count 3.2: Serto... Histology
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Chondrocyte Cell type
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
Mannitol Compound treatment
1
Osteoblast Cell type
1
Met5A Cell line
1
Testis Organism part
1
Macaca mulatta Organism
1
Ischemic cardiomyopathy Disease state
1
Primary Disease staging
1
Filtered air Compound treatment
1
Colorectal adenocarcinoma Disease state
1
Spermatocyte Cell type
1
Fu97 Cell line
1
Skeletal muscle Organism part
1
A549 Cell line
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
Poorly differentiated gastric ... Disease state
1
Uninfected Infection
1
Term Developmental stage
1
Midgestation Developmental stage
1
Pancreatic cancer Disease state
1
CD3int CD4+ CD8+ Phenotype
1
Double positive thymocyte Cell type
1
None Compound treatment
1
Granulocyte-colony stimulating... Compound treatment
1
MKN45 Cell line
1
MKN28 Cell line
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Papillary thyroid carcinoma Disease state
1
TMK1 Cell line
1
Seminiferous tubule Organism part
1
PT4a Disease staging
1
Idiopathic dilated cardiomyopa... Disease state
1
Adipose-derived stem cell Cell type
1
Lung Organism part
1
CD3high CD4+ CD8- Phenotype
1
Single positive thymocyte Cell type
1
AZ521 Cell line
1
Cartilage Organism part
1
Homo sapiens Organism
1
Thymus Organism part
1
CD3- CD4+ CD8- Phenotype
1
Intrathymic T progenitor cell Cell type
1
Johnsen score count 7: many ea... Histology
1
Molecular class type 1 Test result
1
Molecular class type 2 Test result
1
Astrocyte Cell type
1
Benign Disease staging
1
Atrioventricular node Organism part
1
Kaposi's sarcoma Disease state
1
A. fumigatus condia in media Growth condition
1
Ciliary ganglion Organism part
1
Vulvar intraepithelial neoplas... Disease state
1
Kaposi's sarcoma-associated he... Infection
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
NCI-N87 Cell line
1
Bone marrow Organism part
1
SNU5 Cell line
1
Whole blood Organism part
1
HTERT/HPVE6/HPVE7 transfection Gene modification
1
Endothelial cell Cell type
1
Pan troglodytes Organism
1
KatoIII Cell line
1
Grade II Tumor grading
1
None Gene modification
1
Severe inflammation Disease staging
1
Tumor Organism part
1
0 cm away from the tumor bound... Observation
1
Superior cervical ganglion Organism part
1
Actinomycin D Compound treatment
1
Rosiglitazone Compound treatment
1
4 cm away from the tumor bound... Observation
1
Epilepsy Disease state
1
Expression Profiles
E-GEOD-5823: RNAi profiling of human cancer cell lines depleted for c-MYC depletion
Experimental Factors
Disease state RNAi Cell line
Show expression profile  /  experiment details

 
E-GEOD-15460: Transcription profiling of human gastric cancers, cell lines and controls
Experimental Factors
Show expression profile  /  experiment details

 
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