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CTBP1 Homo sapiens
CTBP1 is differentially expressed in 131 experiments [147 up/152 dn]: 42 organism parts: cerebellum [2 up/0 dn], bone marrow [0 up/2 dn], ...; 44 disease states: normal [7 up/10 dn], breast carcinoma [2 up/0 dn], ...; 19 cell types, 35 cell lines, 26 compound treatments and 22 other conditions.
Synonyms CTBP, CTBP1, DKFZp434B0914, hCG_1981976
Orthologs Ctbp1 (Mus musculus)  ctbp-1 (Caenorhabditis elegans)  SER3 (Saccharomyces cerevisiae)  SER33 (Saccharomyces cerevisiae)  CtBP (Drosophila melanogaster)  CTBP1_RAT (Rattus norvegicus)  (Compare orthologs)
InterPro Term D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, NAD(P)-binding domain
GO Terms cytoplasm, interspecies interaction between organisms, metabolic process, negative regulation of transcription from RNA polymerase II promoter, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Uniprot Q13363  Q4KMQ8  Q4W5N3  Q7Z2Q5  Q9NSY3  Q6IP95 
Search EB-eye ENSG00000159692
REST API
Expression Summary
253 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
10
7
None Compound treatment
2
2
Homo sapiens Organism
1
3
Cerebellum Organism part
2
FLAP Compound treatment
2
MK886 Compound treatment
2
Pan troglodytes Organism
2
N/a Test result
2
Breast carcinoma Disease state
2
HNRPA2B Compound treatment
2
Not applicable Histology
2
Female Sex
2
Invasive ductal carcinoma Histology
2
BT-474 Cell line
1
1
Bone marrow Organism part
2
MDA-MB-231 Cell line
1
1
Skeletal muscle Organism part
2
0 cm away from the tumor bound... Observation
2
Uninfected Infection
2
DMSO Vehicle
2
Cystic change Histology
1
1
Control Compound treatment
1
1
MCF-7 Cell line
1
1
Male Sex
1
1
Huntington's disease Disease state
2
Peripheral blood Organism part
1
1
HL-60 Cell line
1
1
SKBR3 Cell line
1
BT474 Cell line
1
MDA468 Cell line
1
Pretreatment primary sample Clinical info
1
Glucocorticoid resistant Phenotype
1
Caudate nucleus Organism part
1
Kidney Organism part
1
Malignant melanoma Disease state
1
SW480 Cell line
1
SW620 Cell line
1
Glucocorticoid sensitive Phenotype
1
ERalpha transfected Genotype
1
ERbeta transfected Genotype
1
MCF7 Cell line
1
T47D Cell line
1
Ovary Organism part
1
Gorilla gorilla Organism
1
White blood cells Organism part
1
X-linked chronic granulomatous Disease state
1
Chronic lymphocytic leukemia Disease state
1
Unknown_sex Sex
1
IgV status unknown Genotype
1
T47-D Cell line
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Tumor Organism part
1
Rapamycin Compound treatment
1
Limited radiation toxicity Clinical history
1
Vascular smooth muscle cell Cell type
1
Epidermal growth factor Compound treatment
1
Skin Organism part
1
Chondrocyte Cell type
1
SKMEL5 Cell line
1
Smooth muscle Organism part
1
Dimethyl sulfoxide Compound treatment
1
BL41K3 Cell line
1
BJABK3 Cell line
1
Endometrioid carcinoma Disease state
1
Fetal bovine serum in media Growth condition
1
IgV mutated Genotype
1
Diagnosed with skin cancer bef... Clinical history
1
Bacterial endotoxin Compound treatment
1
HPL1 Cell line
1
SkinEthic keratinocyte Cell type
1
Epidermal keratinocyte Cell type
1
Macaca mulatta Organism
1
HeLa Cell line
1
Spermatid Cell type
1
Spermatocyte Cell type
1
Carcinoma in situ lesion Disease state
1
Stage I Disease staging
1
Appendix Organism part
1
Methotrexate Compound treatment
1
Acute lymphocytic leukemia Disease state
1
Testis Organism part
1
Endothelial cell Cell type
1
Fibroblast Cell type
1
Trigeminal ganglion Organism part
1
PCep4 control vector transfect... Gene modification
1
ETat plasmid transfection Gene modification
1
BJAB Cell line
1
Pan paniscus Organism
1
Media only Growth condition
1
T-cell lymphoblastic lymphoma Disease state
1
Lymphoid tissue Organism part
1
Superficial transitional cell ... Disease state
1
HaCaT Cell line
1
Stage II Disease staging
1
Affymetrix Labeling Protocol type
1
Uterus corpus Organism part
1
Whole brain Organism part
1
Ciliary ganglion Organism part
1
Idiopathic dilated cardiomyopa... Disease state
1
Lipopolysaccharide Compound treatment
1
Benign nevi Disease state
1
Cartilage Organism part
1
Epilepsy Disease state
1
HMEC184 Cell line
1
Trichostatin A Compound treatment
1
Seminiferous tubule Organism part
1
Carboplatin resistant Test result
1
Carboplatin sensitive Test result
1
Johnsen score count 2: Sertoli... Histology
1
Serum starvation synchronizati... Growth condition
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
Amygdala Organism part
1
GLI60 Cell line
1
Multiple myeloma Disease state
1
SsMCF7 Cell line
1
Geriatric Developmental stage
1
Pediatric Developmental stage
1
Muscle invasive carcinoma Disease state
1
Lymphatic endothelial cell Cell type
1
Duodenum Organism part
1
Cancer15 Replicate
1
GLI72 Cell line
1
Stromal cell Cell type
1
U87 Cell line
1
U373 Cell line
1
Superficial transitional cell ... Disease state
1
B-precursor acute lymphoblasti... Disease state
1
5-aza-2'-deoxycytidine Compound treatment
1
R-(-)-apomorphine HCl Compound treatment
1
Cerebellum peduncles Organism part
1
Heat-killed HL60 cell lysate Infection
1
Postprandial lipid micelles in... Growth condition
1
Inter-prandial lipid micelles ... Growth condition
1
ITS medium Growth condition
1
ITS medium with albumin-bound ... Growth condition
1
White blood cell Cell type
1
Platelet Cell type
1
Organism_part Material type
1
Cell Material type
1
Kaposi's sarcoma Disease state
1
Ulcerative colitis Disease state
1
Cigarette smoke Growth condition
1
Incubator control Growth condition
1
Selenium Compound treatment
1
Superior cervical ganglion Organism part
1
Control for heregulin Compound treatment
1
Drug-naive Clinical treatment
1
Serum starvation + thymidine b... Growth condition
1
Measles virus Chicago-1 strain Infection
1
10 ng/ml LPS in media Growth condition
1
MCF10A Cell line
1
AdERb high moi Gene modification
1
Jurkat Cell line
1
Dorsal root ganglion Organism part
1
Acute radiation toxicity Clinical history
1
IgV unmutated Genotype
1
Ethanol Vehicle
1
Enzo Labeling Protocol type
1
Normal Histology
1
Sapphyrin PCI-2051 Compound treatment
1
KSHV latent infection Disease state
1
Parietal lobe Organism part
1
Beas2B Cell line
1
Training set Population
1
Test set Population
1
HMT3522S1 Cell line
1
AdERb low moi Gene modification
1
Mannitol Compound treatment
1
TaN0M0 Disease staging
1
Johnsen score count 3.2: Serto... Histology
1
Wild_type Genotype
1
BCKN-1 Cell line
1
Osteoblast Cell type
1
Johnsen score count 5: no sper... Histology
1
IMP(1,3)A RNAi
1
Control for EGF Compound treatment
1
MDS-associated acute myeloid l... Disease state
1
Acute myeloid leukemia Disease state
1
Dermatomyositis Disease state
1
Grade 3 Disease staging
1
Grade 3 Disease staging
1
Atrioventricular node Organism part
1
Prefrontal cortex Organism part
1
Placebo Compound treatment
1
Control Disease state
1
Acute promyelocytic leukemia Disease state
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
PC3 Cell line
1
CD4+ T cell Cell type
1
CD8+ T cell Cell type
1
Burkitt's lymphoma Disease state
1
Decrease in CD4 cells Clinical history
1
Occipital lobe Organism part
1
Breast cancer Disease state
1
Cervical cancer Disease state
1
Primary gastric tumor Organism part
1
Adult Developmental stage
1
Infant Developmental stage
1
Capra hircus Organism
1
Sapphyrin PCI-2055 Compound treatment
1
M1 macrophage Cell type
1
Met5A Cell line
1
Interferon-gamma + lipopolysac... Compound treatment
1
Psoriatic lesional biopsy Clinical info
1
Uninvolved biopsy Clinical info
1
Pancreas Organism part
1
17-allylamino-geldanamycin Compound treatment
1
Slow disease progression Clinical history
1
Primary fibroblast Cell type
1
Mycobacterium tuberculosis Infection
1
Drug regimen not indicated Clinical treatment
1
JMN1B Cell line
1
Cornea epithelium Organism part
1
Conjunctival epithelium Organism part
1
Frontal cortex, primary motor ... Organism part
1
Pons Organism part
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
Liver Organism part
1
Cigarette smoke Compound treatment
1
Leishmania major Infection
1
Filtered air Compound treatment
1
SM1 Cell line
1
Ductal carcinoma in situ Disease state
1
Invasive ductal carcinoma Disease state
1
Idiopathic cardiomyopathy Disease state
1
Neutrophil Cell type
1
Grade IV Tumor grading
1
Low grade glioblastoma Disease state
1
Experimental malaria-infected Disease state
1
Cancer3 Replicate
1
Stage IV/3 Disease staging
1
Johnsen score count 10: full s... Histology
1
Down syndrome Disease state
1
Glioblastoma Disease state
1
Vasectomized Clinical history
1
Globus pallidus Organism part
1
Non-ischemic cardiomyopathy Disease state
1
Monocyte Cell type
1
A. fumigatus condia in media Growth condition
1
Actinomycin D Compound treatment
1
Astrocytoma Disease state
1
Esophageal adenocarcinoma Disease state
1
T3bN1M0 Disease staging
1
Viral load low Clinical history
1
Prostate Organism part
1
Testis - interstitial Organism part
1
Vulvar intraepithelial neoplas... Disease state
1
Intraepithelium Organism part
1
Expression Profiles
E-MEXP-440: Transcription profiling of lapatinib treated of breast cancer cell lines
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
E-GEOD-4646: Transcription profiling of human HUVEC cells infected with Neisseria meningitidis wild type and mutants vs uninfected sampled at 3 time points
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-GEOD-1725: Transcription profiling of human lymphoblastoid cells from patients with limited or acute radiation toxicity, skin cancer patients and normal controls, exposed to UV or IR light
Experimental Factors
Individual Light Clinical history
Show expression profile  /  experiment details

 
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