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Hnf4a Mus musculus
Hnf4a is differentially expressed in 91 experiments [108 up/109 dn]: 52 organism parts: liver [17 up/0 dn], kidney [7 up/1 dn], ...; 3 disease states: normal [1 up/1 dn], lung adenocarcinoma [1 up/0 dn], ...; 24 cell types, 13 compound treatments, 18 developmental stages and 11 other conditions.
Synonyms Hnf-4, Hnf4, Hnf4a, Tcf14, Nr2a1
Orthologs nhr-35 (Caenorhabditis elegans)  nhr-31 (Caenorhabditis elegans)  nhr-64 (Caenorhabditis elegans)  HNF4A (Homo sapiens)  HNF4A_RAT (Rattus norvegicus)  nhr-3 (Caenorhabditis elegans)  nhr-88 (Caenorhabditis elegans)  nhr-69 (Caenorhabditis elegans)  nhr-49 (Caenorhabditis elegans)  nhr-97 (Caenorhabditis elegans)  Hnf4 (Drosophila melanogaster)  hnf4a (Danio rerio)  (Compare orthologs)
InterPro Term Nuclear hormone receptor, ligand-binding, Nuclear hormone receptor, ligand-binding, core, Retinoid X receptor, Zinc finger, nuclear hormone receptor-type, Steroid hormone receptor
GO Terms RNA polymerase II transcription factor activity, enhancer binding, glucose homeostasis, positive regulation of gene-specific transcription from RNA polymerase II promoter, regulation of gastrulation, response to glucose stimulus
Uniprot P49698 
Search EB-eye ENSMUSG00000017950
REST API
Expression Summary
154 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Liver Organism part
17
Wild_type Genotype
6
3
Kidney Organism part
1
7
Embryonic stem cell Cell type
2
2
Embryo Developmental stage
3
1
Spleen Organism part
3
Hypothalamus Organism part
3
Testis Organism part
3
Adult Developmental stage
3
Hematopoietic stem cell Cell type
3
Hippocampus Organism part
1
2
C57BL/6J Strain or line
2
1
None Compound treatment
1
2
Ovary Organism part
2
Lung Organism part
2
Adipose tissue Organism part
2
Colon Organism part
1
1
Pancreas Organism part
2
E15.5 Developmental stage
2
Normal Disease state
1
1
Somatic cell Cell type
1
1
Uninfected Infection
1
1
Control Compound treatment
1
1
Amygdala Organism part
1
Large intestine Organism part
1
CBA/CaJ Strain or line
1
Small intestine Organism part
1
Skeletal muscle Organism part
1
Quadriceps skeletal muscle Organism part
1
Medial gastrocnemius Organism part
1
Quadriceps muscle Organism part
1
Partial hepatectomy Injury
1
Anterior tibialis Organism part
1
Ileum Organism part
1
Snout epidermis Organism part
1
Spermatid Cell type
1
Jejunum Organism part
1
Allergen Compound treatment
1
Control - PBS Compound treatment
1
Bmal1-/- Genotype
1
E12.5 Developmental stage
1
Submandibular gland Organism part
1
Neural Observation
1
Non-neural Observation
1
Spermatogonium Cell type
1
SCA1 knock-in Genotype
1
Neural stem/progenitor cell Cell type
1
SCA1 wild_type Genotype
1
Corpus Organism part
1
Myeloid progenitor cell Cell type
1
E12 Developmental stage
1
E8.5 Developmental stage
1
Constant darkness Light
1
12 h light:12 h dark Light
1
52.2 kcal per wk for 8 wk Growth condition
1
Lung adenocarcinoma Disease state
1
GABAergic interneuron Cell type
1
8-cell Developmental stage
1
T regulatory cells anti-ICOS-t... Cell type
1
Bone marrow Organism part
1
Stomach Organism part
1
CREM(-/-) Genotype
1
Preoptic Organism part
1
Thymus Organism part
1
TICAM1(-/-) Genotype
1
E13.5 Developmental stage
1
Dibenzazepine Compound treatment
1
SCA7 wild_type Genotype
1
SCA7 knock-in Genotype
1
Trachea Organism part
1
Pancreatic islet Organism part
1
Primary osteoblast Cell type
1
Cycloheximide (pretreatment)+ ... Compound treatment
1
GABAergic neuron Cell type
1
Sertoli cell Cell type
1
T8 spindal segment Organism part
1
Trypanosoma congolense Infection
1
Vagina Organism part
1
Cerebellum Organism part
1
Sham surgery Injury
1
Castration Injury
1
Main olfactory epithelium Organism part
1
Site of trauma Observation
1
Bone Organism part
1
Control Infection
1
Mycobacterium tuberculosis Infection
1
Oviduct Organism part
1
Granulocyte-macrophage progeni... Cell type
1
Synovial sarcoma Disease state
1
Digits Organism part
1
Chlorophenylthio-cAMP + glucos... Compound treatment
1
Uterus Organism part
1
Thyroid Organism part
1
Glutamatergic neuron Cell type
1
Pachytene spermatocyte Cell type
1
Cardiomyocyte Cell type
1
E16.5 Developmental stage
1
2-cell Developmental stage
1
Adrenal gland Organism part
1
CpG Compound treatment
1
Blastocyst Developmental stage
1
Cingulate cortex homogenate Organism part
1
Late (42 weeks) Disease staging
1
Primordial germ cell Cell type
1
Epidermis Organism part
1
Th1 Cell type
1
Th2 Cell type
1
AKT transgenic Genotype
1
Interferon-gamma Compound treatment
1
Epiblast Cell type
1
Yersinia enterocolitica WA(pTT... Infection
1
77 kcal for 2 wk, 52.2 kcal fo... Growth condition
1
Cpr-lox control Genotype
1
P16 Developmental stage
1
E18 Developmental stage
1
Cardiotoxin Compound treatment
1
Litter 2 Generation
1
Litter 1 Generation
1
P48-Cre;KrasG12D;Ela-Tgfa Genotype
1
DBA/2J Strain or line
1
Pituitary gland Organism part
1
Virgin Developmental stage
1
Parous Developmental stage
1
Heart Organism part
1
Vomeral nasal organ Organism part
1
Feed control Compound treatment
1
Chimpanzee diet Growth condition
1
P23 Developmental stage
1
PGC-1 beta transgenic Genotype
1
Female Sex
1
Male Sex
1
Cytarabine sensitive Phenotype
1
Cytarabine resistant Phenotype
1
Ara-C Compound treatment
1
Umbilical cord Organism part
1
PGC-1alpha null Genotype
1
Primary dermal fibroblast Cell type
1
Cortex Organism part
1
Rb-/- Genotype
1
E10.5 Developmental stage
1
Cerebral cortex Organism part
1
Oocyte Organism part
1
Epiblast stem cell (EpiSC) Cell type
1
CD45+ Cell type
1
CD45- Cell type
1
Pituitary Organism part
1
LSK, Flk2- Ncad- Phenotype
1
R848 Compound treatment
1
1-cell Developmental stage
1
Genital ridge/mesonephros Organism part
1
Whole heart Organism part
1
Tcf1-/- Genotype
1
SCD1 -/- Genotype
1
Hnf4a null Genotype
1
Expression Profiles
E-MEXP-1190: Transcription profiling time series of kidney, liver and spleen from three strains of mice infected with Trypanosoma congolense to investigate strain differences in susceptibility
Experimental Factors
Time Organism part Infection Strain or line
Show expression profile  /  experiment details

 
E-GEOD-3594: Transcription profiling of twenty four mouse neural tissues and ten body regions from five inbred strains to build a gene expression-based brain map
Experimental Factors
Observation Organism part Strain or line
Show expression profile  /  experiment details

 
E-GEOD-3963: Transcription profiling of hippocampus and amygdala from naive, conditioned and fear stimuls exposted mice
Experimental Factors
Clinical treatment Organism part
Show expression profile  /  experiment details

 
E-MEXP-114: Transcription profiling of hypothalamus, liver, kidney, ovaries and testis from male and female humans and mice
Experimental Factors
Sex Organism Organism part
Show expression profile  /  experiment details

 
E-AFMX-4: Transcription profiling of mouse cell types and tissues (GNF/Novartis)
Experimental Factors
Organism part Developmental stage
Show expression profile  /  experiment details

 
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