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InterPro Team Home Page
The InterPro Team is headed by Sarah
Hunter
The team is part of the PANDA Group and is responsible for the maintenance of
the InterPro and CluSTr projects and the development
of a new European resource for metagenomics.
InterPro
InterPro (http://www.ebi.ac.uk/interpro/) is an
integrated documentation resource for protein families, domains and functional sites. The project
integrates protein signatures from Pfam, PRINTS, PROSITE, ProDom, TIGRFAMs, PIRSF, SUPERFAMILY,
Gene3D, PANTHER and HAMAP. As well as grouping together related signatures, InterPro adds
biological annotation and provides links to external databases such as GO, PDB, SCOP, CATH and
ENZYME. All InterPro matches to UniProt proteins are calculated monthly using the InterProScan
software (http://www.ebi.ac.uk/Tools/InterProScan/), and
displayed in InterPro entries in various formats. InterPro has a number of important applications,
including protein functional classification and automatic annotation of proteins for UniProtKB and
genome annotation projects.
Metagenomics
EBI is developing a portal for the archiving, analysis and integration of metagenomics data. A site
containing information about how to submit metagenomics projects to EBI is available at http://www.ebi.ac.uk/metagenomics/. This site will
develop further to include analysis and browsing capabilities during 2010.
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