IPD - MHC Database

Non-Human Primate (NHP) Nomenclature

Welcome to the NHP database, a specialist database for the Major Histocompatibility Complex genes of Non-Human Primates. The database includes Apes and both Old World and New World monkeys. It presently covers over 44 different primate species, and is subject to quality control.

Incorporated in the database are currently known and annotated (full-length, or minimal exons 2 and 3) MHC class I sequences, and (full-length, or minimal exon 2) MHC class II sequences. Various authors have published the sequences. Deduced protein alignments of all sequences are available.

The NHP project was previously known as the IMGT/NHP Database as during the starting up state was sponsored in part by the ImMunoGeneTics information system (IMGT).

Getting Started

From the left-hand menu bar choose "Alignment". In the field that appears you get the option to select a species and locus. Additionally, it is possible to choose a nucleotide or an amino acid alignment. For help press the "Help" button at the end of each particular box. Press the "Align sequence now" button to get an alignment. To do another alignment choose "Sequence Alignments" at the top of the page.

For additional information on the sequences, choose "Nomenclature" in the left-hand menu bar. Under the header “Nomenclature reports”, the different species included in the database are listed. Click on the species required and a list of available loci will appear. Click on the required locus. This will bring you to a table with specific information. The accession numbers and references in the table are linked to the original database and PubMed, respectively.

Further Information

For more information on the NHP nomenclature please contact ipdmhc.nhp@bprc.nl.For information regarding the website and technical issues please contact IPD Support.