IPD-MHC Non-Human Primates (NHP)

Welcome to the NHP database, a specialist database for the Major Histocompatibility Complex genes of Non-Human Primates. The database includes Apes and both Old World and New World monkeys. It presently covers over 40 different primate species and is subject to quality control.

At present we are making and implementing adjustments to the database. As a consequence the on-line Release 1.10.0, including the alleles submitted in the last part of 2013 and in 2014, is postponed. The database is undergoing a major rebuild to cope with the updated information and to stream-line the release process

At the current time the newly named alleles are not available throught the website, although, most of them are already designated and archived by the curators, and are accessible via the Genbank/EMBL-ENA/DDBJ databases. To provide our users with access to these files, we are including FASTA formatted files of the newly available and updated sequences via the download tool of the website (ftp.ebi.ac.uk/pub/databases/ipd/mhc/nhp). The main website will remain static while the redevelopment work is undertaken and the FASTA files updated to ensure publication of the new allele names.

Should the need for an overview of alleles of a certain locus arise, please feel free to contact us. We can provide custom made tables displaying the most recent information.

We apologize for the inconvenience that this may cause and hope to report as soon as possible the Release 1.10.0 is on-line.

Nel Otting and Natasja de Groot
(ipdmhc.nhp@bprc.nl)

For allele designation the database uses the 2010 nomenclature rules described by the WHO Nomenclature Committee for Factors of the HLA System.

Curation

The alignments used have been curated by;

Natasja de Groot, Nel Otting and Ronald Bontrop
Biomedical Primate Research Centre
Lange Kleiweg 139
RIJSWIJK
The Netherlands

Tel: +31 15 284 2699
Fax: +31 15 284 3999
Email: Natasja de Groot (ipdmhc.nhp@bprc.nl)
URL: http://www.bprc.nl/

Publications

We hope you will cite the IPD-MHC NHP database whenever you publish your sequences. When citing the database you can use the following articles.

  • Robinson J, Waller MJ, Stoehr P, Marsh SGE
    IPD-the Immuno Polymorphism Database
    Nucleic Acids Research (2013) 41:D1222-7
    (Download PDF File)

  • de Groot NG, Otting N, Robinson J, Blancher A, Lafont BAP, Marsh SGE, O'Connor DH, Shiina T, Walter L, Watkins DI, Bontrop RE
    Nomenclature report on the major histocompatibility complex  genes and alleles of Great Ape, Old and New World monkey species
    Immunogenetics (2012), 64 (8): 615-631

IPD-MHC NHP

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