IPD-MHC Database

Welcome to the IPD-MHC FISH database, a specialist database for the Major Histocompatibility genes of teleost fish. The database includes at present two salmonid species: Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).

Atlantic salmon and rainbow trout possess a single classical MHC class I locus, UBA, and a single classical MHC class II locus consisting of closely linked DAA (IIA) and DAB (IIB). Included in the database are full-length and nearly complete peptide binding domain-coding sequences from published studies and from the EMBL and NCBI databases.

For those readers who would like to know more about MHC sequences in salmonids, please see the Introduction to the Salmonid MHC page.

This database was initiated and maintained from 2006 to 2007 by Prof. René J.M. Stet, who sadly passed away in the middle of a career highlighted by many essential contributions to the field of fish MHC research.

• Parham P
  René Stet: 1954-2007
  Immunogenetics (2008) 60:73-75
• Dixon B
  René Stet's impact on the study of teleost major histocompatibility genes: evolution from loci to populations
  Immunogenetics (2008) 60:77-82

From April 2011 this database is maintained by Dr. Hans (J.M.) Dijkstra, assisted by Dr. Unni Grimholt and Dr. John D. Hansen.

The alignments used are curated by;

Hans Dijkstra

Institute for Comprehensive Medical Science
Division of Biomedical Polymer Science
Fujita Health University
Japan

Email: Dijkstra@fujita-hu.ac.jp