IPD - KIR Database

Release 2.4.0, 15 April 2011

The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

This work was supported by National Institutes of Health Grant P01-CA-111412.

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The first volume of Nucleic Acids Research in 2010 is dedicated to factual databases in the field of molecular biology and contains the following paper on IPD.

• Robinson J, Mistry K, McWilliam H, Lopez R, Marsh SGE
  IPD - the Immuno Polymorphism Database
  Nucleic Acids Research (2010), 38: D863-9
  Full Text available from Nucleic Acids Research or Download PDF File
  
  
• For further IPD publications, please see our citations page.

Latest Developments

• Fully Sequenced KIR Haplotypes New
• Donor KIR B-content group calculator New
• Allele Ethnicity Tool
• Standard Reporting Format for KIR Genotyping Data
• KIR Probe and Primer Search Tool

Developers

Development of the KIR Database has been undertaken by the following individuals and funded by an NIH P01 grant, P01CA111412.

Further Information

For more information about the database, queries (including website) please contact IPD Support.

Please see our licence for terms of use.