IPD - KIR Database

Release 2.1.0, 20 February 2009

The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

This work was supported by National Institutes of Health Grant P01-CA-111412.

• What's new in the latest release of the database
• View the latest database statistics

Latest Developments

• Allele Ethnicity Tool
• Standard Reporting Format for KIR Genotyping Data
• KIR Probe and Primer Search Tool

Developers

Development of the KIR Database has been undertaken by the following individuals.

• Anthony Nolan Research Institute
  • James Robinson
  • Kavita Mistry
  • Christian A Garcia
  • Steven GE Marsh

• Stanford University Medical School
  • Libby Guethlein
  • Peter Parham

• European Bioinformatics Institute
  • Peter Stoehr

Further Information

For more information about the database, queries (including website) please contact IPD Support.