IPD - IMGT/HLAVersion Report - 2.14.1 (2006-08)
The following changes have been made to Release 2.14.0 to address errors in the naming of the following sequences.
| Deleted Sequences | ||||
|---|---|---|---|---|
| Allele | IMGT/HLA Acc No | Date | EMBL/Genbank | Comments |
| A*0298 | HLA02507 | 2006-04-30 | AY897620 |
Sequence named in error and shown to be identical to A*0296 (Aug 06) |
| Cw*0422 | HLA02592 | 2006-06-30 | DQ648008 |
Sequence named in error and shown to be identical to Cw*0421 (Aug 06) |
Version Report - 2.14.0 (2006-07)
Release 2.14.0 is the first to address the problem of representing alleles with aberrant splice sites to the reference sequence. We have previously not marked the exon borders for differently spliced alleles like A*0111N, A*03010102N, A*29010102N and B*44020102S. As a result of this in the current release the cDNA and protein sequences for the above alleles have been modified, for more details please see the Help Page on Splice Site Variants.
| New Sequences | ||||
|---|---|---|---|---|
| Allele | IMGT/HLA Acc No | Date | EMBL/Genbank | Comments |
| A*010104 | HLA02540 | 2006-04-30 | DQ485722 |
|
| A*0120 | HLA02537 | 2006-04-30 | AM183561 |
|
| A*0297 | HLA02509 | 2006-04-30 | DQ409217 |
|
| A*0298 | HLA02507 | 2006-04-30 | AY897620 |
Deleted in Release 2.14.1 |
| A*0299 | HLA02529 | 2006-04-30 | DQ465611 |
|
| A*030105 | HLA02576 | 2006-05-31 | AM261460 |
|
| A*0323 | HLA02528 | 2006-04-30 | DQ465612 |
|
| A*0324 | HLA02590 | 2006-05-31 | DQ403156 DQ403157 |
|
| A*1124 | HLA02386 | 2005-11-23 | AM114414 |
|
| A*1127 | HLA02530 | 2006-04-30 | DQ465608 |
|
| A*1128 | HLA02533 | 2006-04-30 | DQ473291 |
|
| A*2463 | HLA02524 | 2006-04-30 | AB253623 |
|
| A*2464 | HLA02574 | 2006-05-31 | AF030911 DQ523225 |
|
| A*2465 | HLA02608 | 2006-06-30 | AM268430 |
|
| A*2466 | HLA02613 | 2006-06-30 | DQ782329 |
|
| A*2505 | HLA02607 | 2006-06-30 | DQ645957 |
|
| A*2631 | HLA02581 | 2006-05-31 | DQ530236 |
|
| A*3017 | HLA02510 | 2006-04-30 | DQ409216 |
|
| A*68020102 | HLA02508 | 2006-04-30 | AM235886 |
|
| A*6833 | HLA02531 | 2006-04-30 | DQ438173 DQ438174 DQ438175 |
|
| A*6834 | HLA02595 | 2006-06-30 | DQ648004 |
|
| A*9201 | HLA02538 | 2006-04-30 | DQ473292 |
|
| A*9203 | HLA02582 | 2006-05-31 | DQ485737 |
|
| B*0748 | HLA02514 | 2006-04-30 | DQ455017 |
|
| B*0749N | HLA02519 | 2006-04-30 | AM236599 |
|
| B*0750 | HLA02560 | 2006-05-31 | AM236590 |
|
| B*0830N | HLA02591 | 2006-06-30 | DQ641496 |
|
| B*1316 | HLA02516 | 2006-04-30 | DQ455015 |
|
| B*2736 | HLA02513 | 2006-04-30 | DQ455018 DQ455019 |
|
| B*350106 | HLA02566 | 2006-05-31 | DQ514598 |
|
| B*3562 | HLA02385 | 2005-11-23 | AM114412 |
|
| B*3712 | HLA02532 | 2006-04-30 | DQ473294 |
|
| B*3814 | HLA02584 | 2006-05-31 | AM261745 |
|
| B*3937 | HLA02384 | 2005-11-23 | AM114413 |
|
| B*4066 | HLA02536 | 2006-04-30 | DQ181794 |
|
| B*4067 | HLA02588 | 2006-05-31 | AB257503 |
|
| B*4068 | HLA02597 | 2006-06-30 | DQ647703 |
|
| B*4816 | HLA02517 | 2006-04-30 | DQ455014 DQ455014 |
|
| B*5142 | HLA02558 | 2006-05-31 | AM260212 |
|
| B*5210 | HLA02585 | 2006-05-31 | DQ537945 |
|
| B*5521 | HLA02518 | 2006-04-30 | DQ455012 |
|
| B*5522 | HLA02539 | 2006-04-07 | DQ458812 DQ458813 DQ458814 |
|
| B*5617 | HLA02565 | 2006-05-31 | DQ514600 |
|
| B*5812 | HLA02512 | 2006-04-30 | DQ455013 DQ455020 |
|
| B*5813 | HLA02596 | 2006-06-30 | DQ648737 |
|
| B*5902 | HLA02589 | 2006-05-31 | AB257504 |
|
| B*9515 | HLA02515 | 2006-04-30 | DQ455016 |
|
| B*9516 | HLA02545 | 2006-04-30 | AM259370 |
|
| Cw*0215 | HLA02559 | 2006-05-31 | AM260635 |
|
| Cw*0216 | HLA02593 | 2006-06-30 | DQ648007 |
|
| Cw*030305 | HLA02567 | 2006-05-31 | DQ514597 |
|
| Cw*030405 | HLA02522 | 2006-04-30 | DQ417102 DQ417103 |
|
| Cw*0326 | HLA02526 | 2006-04-30 | AB253624 |
|
| Cw*0327 | HLA02594 | 2006-06-30 | DQ648006 |
|
| Cw*0328 | HLA02599 | 2006-06-30 | AB257505 |
|
| Cw*0329 | HLA02600 | 2006-06-30 | AB257506 |
|
| Cw*0419 | HLA02511 | 2006-04-30 | DQ453525 |
|
| Cw*0420 | HLA02525 | 2006-04-30 | DQ417108 DQ417109 |
|
| Cw*0421 | HLA02578 | 2006-05-31 | DQ525630 DQ648008 |
|
| Cw*0422 | HLA02592 | 2006-06-30 | DQ648008 |
Deleted in Release 2.14.1 |
| Cw*0514 | HLA02586 | 2006-05-31 | DQ535033 DQ535035 |
|
| Cw*06020102 | HLA02561 | 2006-05-31 | DQ249182 |
Genomic sequence |
| Cw*070106 | HLA02523 | 2006-04-30 | DQ417104 DQ417105 |
|
| Cw*070107 | HLA02611 | 2006-06-30 | DQ782328 |
|
| Cw*0739 | HLA02564 | 2006-05-31 | DQ514599 |
|
| Cw*1218 | HLA02527 | 2006-04-30 | DQ465613 |
|
| Cw*1219 | HLA02605 | 2006-06-30 | AM261030 |
|
| Cw*1408 | HLA02427 | 2006-01-27 | DQ314861 |
|
| DPB1*1702 | HLA02451 | 2006-02-22 | DQ206450 DQ206450 DQ206450 |
|
| DPB1*1902 | HLA02579 | 2006-05-31 | DQ485789 |
|
| DQB1*060403 | HLA02602 | 2006-06-30 | DQ503425 |
|
| DQB1*060802 | HLA02609 | 2006-06-30 | AM279416 |
|
| DRB1*0330 | HLA02603 | 2006-06-30 | AM269468 |
|
| DRB1*0331 | HLA02606 | 2006-06-30 | DQ666333 |
|
| DRB1*0458 | HLA02534 | 2006-04-28 | DQ473290 |
|
| DRB1*0459 | HLA02580 | 2006-05-31 | DQ525631 |
|
| DRB1*115402 | HLA02568 | 2006-05-31 | DQ514604 |
|
| DRB1*1156 | HLA02577 | 2006-05-31 | DQ525634 |
|
| DRB1*1157 | HLA02587 | 2006-05-31 | DQ535034 |
|
| DRB1*1215 | HLA02583 | 2006-05-31 | DQ533486 |
|
| DRB1*1372 | HLA02535 | 2006-04-28 | DQ473293 |
|
| DRB1*1373 | HLA02570 | 2006-05-31 | DQ514602 |
|
| DRB1*1374 | HLA02610 | 2006-06-30 | AM279417 |
|
| DRB1*1459 | HLA02520 | 2006-04-28 | AM233907 |
|
| DRB1*1460 | HLA02563 | 2006-05-31 | AM259285 |
|
| DRB1*1461 | HLA02572 | 2006-05-31 | DQ494324 |
|
| DRB1*1462 | HLA02612 | 2006-06-30 | DQ782331 |
|
| DRB1*150106 | HLA02569 | 2006-05-31 | DQ514601 DQ514603 |
|
| DRB1*1520 | HLA02571 | 2006-05-31 | AM258966 |
|
| DRB1*1521 | HLA02573 | 2006-05-31 | DQ525633 |
|
| DRB1*1522 | HLA02575 | 2006-05-31 | DQ525632 |
|
| H*01010101 | HLA02546 | 2006-04-30 | AF055066 CR388220 M32106 |
Genomic sequence |
| H*01010102 | HLA02557 | 2006-04-30 | X12432 |
Genomic sequence |
| H*01010103 | HLA02548 | 2006-04-30 | M31944 |
Genomic sequence |
| H*0102 | HLA02551 | 2006-04-30 | AL845454 |
Genomic sequence |
| H*02010101 | HLA02547 | 2006-04-30 | AB023057 AL671561 CT009496 |
Genomic sequence |
| H*02010102 | HLA02549 | 2006-04-30 | M96336 |
Genomic sequence |
| H*0202 | HLA02556 | 2006-04-30 | AC004194 BX927141 |
Genomic sequence |
| H*0203 | HLA02550 | 2006-04-30 | BX284699 |
Genomic sequence |
| H*0204 | HLA02552 | 2006-04-30 | AL645929 |
Genomic sequence |
| H*0205 | HLA02554 | 2006-04-30 | M32105 |
Genomic sequence |
| H*0206 | HLA02555 | 2006-04-30 | J00191 |
Genomic sequence |
| H*0301 | HLA02553 | 2006-04-30 | M32104 |
Genomic sequence |
| Sequences Pending | ||||
| Allele | IMGT/HLA Acc No | Date | EMBL/Genbank | Comments |
| A*1129 | ||||
| A*2629 | ||||
| A*2630 | ||||
| A*2915 | ||||
| A*680105 | ||||
| A*9202 | ||||
| Cw*0740 | ||||
| DRB1*0460 | ||||
| Modified Sequences | ||||
| Allele | IMGT/HLA Acc No | Date | EMBL/Genbank | Comments |
| A*0111N | HLA02057 | 2005-01-31 | AY574934 AY836150 |
The last 24 bases of exon 3 have been marked as removed from the CDS due to a mutation in the splice site that causes this exon to end prematurely. Protein sequence modified. |
| A*03010102N | HLA01718 | 2003-02-25 | AJ532608 AM041067 AM041068 |
Sequence extended to include additional 62 bps due to mutation in the splice site at the end of exon 4. Protein sequence modified. |
| A*260101 | HLA00073 | 1989-08-01 | AL845454 D16843 D32130 D32131 M24095 U03697 |
Genomic sequence added |
| A*29010102N | HLA01406 | 2001-01-31 | AJ293507 |
Sequence extended to include additional 65 bps due to mutation in the splice site at the end of exon 4. Protein sequence modified. |
| B*0710 | HLA00142 | 1998-07-28 | AJ223602 AM236752 |
Sequence extended from position 620 to 895 |
| B*0717 | HLA01110 | 1999-11-18 | AB256953 AF173936 |
Sequence extended from position 620 to 895 |
| B*15010101 | HLA00162 | 1989-08-01 | AF436090 AJ295140 D50292 DQ249177 L48400 L79939 M28203 M83193 U03859 |
Genomic sequence extended to cover 5' UTR |
| B*15010102N | HLA00163 | 1998-12-07 | AJ250917 AM048844 Y17110 |
Genomic sequence has had 28 bps of primer sequence removed from gDNA positions -28 to -1 |
| B*15170101 | HLA00180 | 1993-08-09 | AJ300181 U01848 U35431 |
Genomic sequence has had 28 bps of primer sequence removed from gDNA positions -28 to -1 |
| B*3517 | HLA00254 | 1995-11-16 | AB256954 L49341 L75941 U34618 |
Sequence extended from position 620 to 895 |
| B*380101 | HLA00267 | 1989-08-01 | DQ249175 DQ249179 L36591 M29864 U40498 |
Genomic sequence extended |
| B*40060101 | HLA00297 | 1992-08-13 | AJ300180 M95531 |
Genomic sequence has had 28 bps of primer sequence removed from gDNA positions -28 to -1 |
| B*4402102S | HLA01606 | 2002-05-31 | AF384095 | The nucleotide sequence of exon 5, positions 896 to 1012, has been removed from the CDS as it is not expressed due to a mutation in intron 4. Protein sequence modified. |
| B*4446 | HLA02343 | 2005-09-23 | AM236591 DQ185396 |
Sequence extended from position 1 to 73 and position 620 to 1089 Genomic sequence extended |
| B*5001 | HLA00341 | 1991-11-14; | DQ249182 U11261 X61706 |
Genomic sequence extended |
| B*5610 | HLA01658 | 2002-09-30 | AB254370 AY134744 |
Sequence extended from position 620 to 895 |
| B*7805 | HLA01403 | 2000-12-18 | AB051357 AB254369 |
Sequence extended from position 620 to 895 |
| Cw*030401 | HLA00413 | 1992-08-14 | D64150 DQ249177 M99389 U31372 U31373 U44064 |
Genomic sequence added |
| Cw*06020101 | HLA00430 | 1992-10-07 | AJ420245 D64147 DQ249180 M28160 M28206 X70857 Z22752 Z22753 Z22754 |
Genomic sequence extended to cover 5' UTR |
| Cw*0802 | HLA00446 | 1991-11-14 | DQ249173 DQ249176 M59865 M84173 |
Genomic sequence extended |
| DRB1*1331 | HLA00829 | 1997-03-06 | DQ525629 U88133 U88134 |
* -> G, position 370 |
| MICA*01802 | HLA02034 | 2004-12-21 | AJ580805 |
G -> *, position 70 |
| MICA*053 | HLA02334 | 2005-09-23 | AJ871399 AJ871399 |
G -> *, position 70 |
| MICB*015 | HLA02075 | 2004-12-10 | AJ563706 |
G -> *, position 70 |
| Deleted Sequences | ||||
| Allele | IMGT/HLA Acc No | Date | EMBL/Genbank | Comments |
| A*0298 | HLA02507 | 2006-04-30 | AY897620 |
Sequence named in error and shown to be identical to A*0296 (Aug 06) |
| Cw*020204 | HLA00407 | 1997-03-19 | U88838 U88839 U97346 U97347 Z96924 |
Sequence shown to be identical to Cw*0210 (Apr 06) |
| Cw*0422 | HLA02592 | 2006-06-30 | DQ648008 |
Sequence named in error and shown to be identical to Cw*0421 (Aug 06) |
IMGT/HLA
Sponsors
