Accessing the IMGT/HLA Database

The IMGT/HLA Database can be accessed a variety of ways. You can query the database using the a number of access methods from the following tables. The more common tools are also available directly from the right hand menu bar.

Query Tools
Allele Query Form Search tool for retrieving information on any allele in the IMGT/HLA Database.
Allele Status Checker Allows users to determine which alleles contain only partial sequences and which alleles have not been independently confirmed.
Cell Queries Search tool which allows complex queries on source cells.
Conversion Tools Tool for converting allele names to the new nomenclature
Deleted Alleles List of deleted allele names, with reason for deletion
Ethnic Origins Search tool which displays the known ethnic origins for HLA Alleles.
HLA Typing Ambiguities Page A PDF file of ambiguous allele combinations seen in sequence based typing is provided for you to download. PDF files may require Adobe Acrobat Reader.
KIR Ligand Calculator Defines HLA-B and HLA-C ligand motifs associated with NK cell alloreactivity.
Polymorphism Search Tool Search tool to identify polymorphic positions in HLA sequences.
Probe and Primer Search Search tool for generating probe and primer hit tables.
Sequence Alignments Interactive sequence alignment tool with help page available.

Static text version of the sequence alignments are available from provided by the HLA Informatics Group.
Submission Tools
Sequence Submission Tool Online submission of sequences to the WHO Nomenclature Committee for Factors of the HLA System.
Other EBI Search Tools
BLAST Search Tool The EBI's BLAST search engine for nucleotide and protein searches.
FASTA Protein Search Tool The EBI's FASTA search engine for protein sequence searches.
Phylogenetic Analysis
ClustalW Phylogenetic analysis of the IMGT/HLA sequences can be performed using ClustalW.



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