Signature

TOP1Ac (SM00437)

Accession SM00437

Integration

DNA topoisomerase, type IA, DNA-binding domain (IPR003602)

Member database

SMART
SMART (a Simple Modular Architecture Research Tool) uses hidden Markov models (HMMs) and allows the identification of genetically mobile domains and the analysis of model architectures. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues.