InterPro results for type:active_site

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N-acetyl-gamma-glutamyl-phosphate reductase, active site (IPR023013) N -Acetylglutamate (NAG) fulfils distinct biological roles in lower and higher organisms. In prokaryotes, lower eukaryotes and plants it is the first intermediate in the biosynthe...

Uracil-DNA glycosylase, active site (IPR018085) Uracil-DNA glycosylase (UNG) is a DNA repair enzyme that excises uracil residues from DNA by cleaving the N-glycosylic bond. Uracil in DNA can arise as a result of mis-incorporat...

Thiolase, active site (IPR020610) Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase . 3-ketoacyl-CoA thiolase (also called thiola...

Serine proteases, trypsin family, histidine active site (IPR018114) This entry represents the histidine active site of serine proteases belonging to the MEROPS peptidase family S1 (chymotrypsin family, clan PA(S)). The catalytic activity of the se...

Phosphoenolpyruvate carboxylase, Lys active site (IPR018129) Phosphoenolpyruvate carboxylase (PEPcase) catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate by bicarbonate to yield oxaloacetate and phosphate. The enzyme is fo...

Thiolase, acyl-enzyme intermediate active site (IPR020615) Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase . 3-ketoacyl-CoA thiolase (also called thiola...

Thymidylate synthase, active site (IPR020940) Thymidylate synthase catalyzes the reductive methylation of dUMP to dTMP with concomitant conversion of 5,10-methylenetetrahydrofolate to dihydrofolate: 5,10-methylenetetrahydrof...

Pectinesterase, Tyr active site (IPR018040) Pectinesterase (pectin methylesterase) catalyses the de-esterification of pectin into pectate and methanol. Pectin is one of the main components of the plant cell wall. In plants...

Ribonucleotide reductase small subunit, acitve site (IPR030475) Ribonucleotide reductase catalyses the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis...

Delta-aminolevulinic acid dehydratase, active site (IPR030656) Delta-aminolevulinic acid dehydratase (ALAD) or porphobilinogen synthase catalyses the second step in the biosynthesis of heme, the condensation of two molecules of 5-aminolevulin...