InterPro results for type:conserved_site

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Gonadotropin-releasing hormone (IPR002012) The gonadotropin-releasing hormones (GnRH) (gonadoliberin) are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary ...

Flagellar motor protein MotA, conserved site (IPR000540) The bacterial protein motA is required for the rotation of the flagellar motor. This protein probably forms a transmembrane proton channel used to energize the flagellar rotary mo...

Sulfatase, conserved site (IPR024607) Sulphatases are enzymes that hydrolyze various sulphate esters. The sequence of different types of sulphatases are available and have shown to be structurally related; these incl...

Prokaryotic lipoprotein-attachment site (IPR032831) In prokaryotes, membrane lipoproteins are synthesised with a precursor signal peptide, which is cleaved by a specific lipoprotein signal peptidase (signal peptidase II). The pepti...

Bax inhibitor 1, conserved site (IPR006213) Bax inhibitor-1 (BI-1) (gene TEGT) is a suppressor of apoptosis that interacts with BCL2 and BCL-X. These are proteins of about 25 kDa which seem to contain seven transmembrane do...

NAD-dependent DNA ligase, conserved site (IPR033136) DNA ligase (polydeoxyribonucleotide synthase) is the enzyme that joins two DNA fragments by catalysing the formation of an internucleotide ester bond between phosphate and deoxyri...

Ribosomal protein L1, conserved site (IPR023673) Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to...

HIRA B motif (IPR019015) The HirA B (Histone regulatory homologue A binding) motif is the essential binding interface between and ASF1a, of approx. 40 residues. It forms an antiparallel beta-hairpin that...

Solute-binding protein family 5, conserved site (IPR023765) Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers a...

Fibrinogen, conserved site (IPR020837) Fibrinogen plays key roles in both blood clotting and platelet aggregation. During blood clot formation, the conversion of soluble fibrinogen to insoluble fibrin is triggered by t...