InterPro results for type:conserved_site

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Zinc finger, XPA-type, conserved site (IPR022652) Xeroderma pigmentosum (XP) is a human autosomal recessive disease, characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this conditio...

Isocitrate/isopropylmalate dehydrogenase, conserved site (IPR019818) Isocitrate dehydrogenase (IDH) is an important enzyme of carbohydrate metabolism which catalyses the oxidative decarboxylation of isocitrate into alpha-ketoglutarate. IDH is eithe...

XPA, conserved site (IPR022658) Xeroderma pigmentosum (XP) is a human autosomal recessive disease, characterised by a high incidence of sunlight-induced skin cancer. Skin cells of individual's with this conditio...

Proliferating cell nuclear antigen, PCNA, conserved site (IPR022659) Proliferating cell nuclear antigen (PCNA), or cyclin, is a non-histone acidic nuclear protein that plays a key role in the control of eukaryotic DNA replication. It acts as a co-f...

Kinesin motor domain, conserved site (IPR019821) Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The kinesin motor activity is directed toward the microtubule's plus end. ...

Large-conductance mechanosensitive channel, conserved site (IPR019823) Mechanosensitive ion channels (MscL) play a critical role in transducing physical stresses at the cell membrane into an electrochemical response. MscL is a protein which forms a c...

Dihydrodipicolinate reductase, conserved site (IPR022664) Dihydrodipicolinate reductase catalyzes the second step in the biosynthesis of diaminopimelic acid and lysine, the NAD or NADP-dependent reduction of 2,3-dihydrodipicolinate into ...

Uricase, conserved site (IPR019842) Uricase (urate oxidase) is the peroxisomal enzyme responsible for the degradation of urate into allantoin: Urate + O2 + H2O = 5-hydroxyisourate + H2O2 Some species, like primate...

Squalene/phytoene synthase, conserved site (IPR019845) Squalene synthase (farnesyl-diphosphate farnesyltransferase) (SQS) and Phytoene synthase (PSY) share a number of functional similarities. These similarities are also reflected a...

Bax inhibitor 1, conserved site (IPR006213) Bax inhibitor-1 (BI-1) (gene TEGT) is a suppressor of apoptosis that interacts with BCL2 and BCL-X. These are proteins of about 25 kDa which seem to contain seven transmembrane do...