InterPro results for type:conserved_site

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Peripherin/rom-1, conserved site (IPR018498) Tetraspanins are a distinct family of proteins, containing four transmembrane domains: a small outer loop (EC1), a larger outer loop (EC2), a small inner loop (IL) and short cytop...

tRNA-dihydrouridine synthase, conserved site (IPR018517) Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukary...

S-adenosylmethionine synthetase, conserved site (IPR022631) S-adenosylmethionine synthetase (MAT) is the enzyme that catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is an important methyl donor for ...

ClpA/B, conserved site 2 (IPR028299) The ClpA/B family of ATP-binding proteins includes the regulatory subunit of the ATP-dependent protease Clp, ClpA; heat shock proteins ClpB, 104 and 78; and chloroplast proteins C...

Orn/DAP/Arg decarboxylase 2, conserved site (IPR022657) These enzymes are collectively known as group IV decarboxylases. Pyridoxal-dependent decarboxylases acting on ornithine, lysine, arginine and related substrates can be classified ...

Aldehyde dehydrogenase, glutamic acid active site (IPR029510) Aldehyde dehydrogenases ( and) are enzymes that oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. In mammals at least four different forms of th...

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 (IPR029752) A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. A...

Pseudouridine synthase TruD, conserved site (IPR020119) Pseudouridine synthase TruD modifies uracil-13 in tRNA. TruD belongs to a recently identified and large family of pseudouridine synthases present in all kingdoms of life. TruD fol...

Shikimate kinase, conserved site (IPR023000) This entry represents shikimate kinase catalyzes the fifth step in the biosynthesis from chorismate of the aromatic amino acids (the shikimate pathway) in bacteria (gene aroK or a...

Claudin, conserved site (IPR017974) Zona occludens (ZO), or tight junctions (TJ), are specialised membrane domains found at the most apical region of polarised epithelial and endothelial cells. They create a primary...