InterPro results for type:active_site

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Aspartic peptidase, active site (IPR001969) Aspartic peptidases, also known as aspartyl proteases , are widely distributed proteolytic enzymes known to exist in vertebrates, fungi, plants, protozoa, bacteria, archaea, retro...

Prokaryotic transglycosylase, active site (IPR000189) Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4- glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation...

Thermonuclease active site (IPR002071) Staphylococcus aureus secretes a thermostable nuclease , known as thermonuclease (TNase), which is a calcium-dependent enzyme that catalyzes the hydrolysis of both DNA and RNA at ...

Peptidase S9, serine active site (IPR002471) Proteolytic enzymes that exploit serine in their catalytic activity are ubiquitous, being found in viruses, bacteria and eukaryotes. They include a wide range of peptidase activit...

Phosphoribosylglycinamide formyltransferase, active site (IPR001555) Phosphoribosylglycinamide formyltransferase (GART) catalyses the third step in de novo purine biosynthesis, the transfer of a formyl group to 5'-phosphoribosylglycinamide. In high...

Phosphoglycerate/bisphosphoglycerate mutase, active site (IPR001345) Phosphoglycerate mutase (PGAM) and bisphosphoglycerate mutase (BPGM) are structurally related enzymes that catalyse reactions involving the transfer of phospho groups between the ...

Lipase, GDXG, putative histidine active site (IPR002168) The following lipolytic enzymes are evolutionary related: Mammalian hormone sensitive lipase (HSL). In adipose tissue and heart, HSL primarily hydrolyzes stored triglycerides to...

Hydroxymethylglutaryl-coenzyme A synthase, active site (IPR000590) Hydroxymethylglutaryl-CoA synthase catalyses the condensation of acetyl-CoA with acetoacetyl-CoA to produce HMG-CoA and CoA, the second reaction in the mevalonate-dependent isopre...

Hydroxymethylglutaryl-CoA lyase, active site (IPR000138) Synonym(s): 3-hydroxy-3-methylglutaryl-coenzyme A synthase, HMG-CoA lyase. HMG-CoA lyase catalyses the transformation of HMG-CoA into acetyl-CoA and acetoacetate. In vertebrates i...

Methylated-DNA-[protein]-cysteine S-methyltransferase, active site (IPR001497) Synonym(s): 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase, Methylated-DNA-[protein]-cysteine S-methyltransferase. This entry represents the activ...