InterPro results for type:active_site

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Glycoside hydrolase, family 16, active site (IPR008263) O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moie...

Ribonucleotide reductase small subunit, acitve site (IPR030475) Ribonucleotide reductase catalyses the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis...

Hydroxymethylglutaryl-coenzyme A synthase, active site (IPR000590) Hydroxymethylglutaryl-CoA synthase catalyses the condensation of acetyl-CoA with acetoacetyl-CoA to produce HMG-CoA and CoA, the second reaction in the mevalonate-dependent isopre...

Phosphoribosylglycinamide formyltransferase, active site (IPR001555) Phosphoribosylglycinamide formyltransferase (GART) catalyses the third step in de novo purine biosynthesis, the transfer of a formyl group to 5'-phosphoribosylglycinamide. In high...

Tyrosine-protein kinase, active site (IPR008266) Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases. Protein kinases c...

4-hydroxybenzoyl-CoA thioesterase, active site (IPR008272) 4-hydroxybenzoyl-CoA thioesterase is an enzyme from Pseudomonas CBS-3, a soil-dwelling microbe that survives on 4-chlorobenzoate as its sole carbon source. This enzyme catalyzes t...

Cysteine peptidase, histidine active site (IPR025660) Thiol (cysteine) proteases (EC 3.4.22.-) are a family of proteolytic enzymes which contain an active site cysteine. Catalysis proceeds through a thioester intermediate and is faci...

Beta-lactamase, class-C active site (IPR001586) This active site signature detects all class C Beta-lactamases. The class C beta-lactamases are serine hydrolases belonging to MEROPS peptidase family S12 (D-Ala-D-Ala carboxypept...

Lipase, GDSL, active site (IPR008265) A variety of lipolytic enzymes with serine as part of the active site have been identified. Protein sequences which contain this active site signature include; Aeromonas hydrophil...

RNA methyltransferase TrmA, active site (IPR030390) This entry represents a conserved region that includes the active site cysteine.In Escherichia coli, the trmA protein is a tRNA (uracil-5-)-methyltransferase that catalyses the S-...