Release notes

Latest release note

v.65
InterPro 65.0
28th September 2017

Features include:

  • New homologous superfamily InterPro entry type.
  • The addition of 1407 InterPro entries.
  • An update to SFLD (3) and PANTHER (12.0).
  • Integration of 4580 new methods from the CDD (232), Pfam (1), SUPERFAMILY (120), PANTHER (4051), CATH-Gene3D (137), PIRSF (24), SFLD (14) and ProDom (1) databases.

Previous release notes

Contents and coverage of InterPro 65.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins.
InterPro release 65.0 contains 32283 entries (last entry: IPR037296), representing:

InterPro cites 53418 publications in PubMed.

Member database information

Signature database Version Signatures* Integrated signatures**
CATH-Gene3D 4.1.0 2737 1366
CDD 3.16 12805 2395
HAMAP 201701.18 2160 2160
PANTHER 12.0 90742 6592
Pfam 31.0 16712 16111
PIRSF 3.02 3285 3223
PRINTS 42.0 2106 1977
ProDom 2006.1 1894 1306
PROSITE patterns 20.132 1309 1289
PROSITE profiles 20.132 1174 1141
SFLD 3 303 143
SMART 7.1 1312 1263
SUPERFAMILY 1.75 2019 1595
TIGRFAMs 15.0 4488 4447

* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release
We use MobiDB-lite, a derivative of the MobiDB database, to provide consensus annotation of long-range intrinsic disorder in protein sequences. Read more about MobiDB-lite in Bioinformatics, 33(9), 2017, 1402–1404, (doi: 10.1093/bioinformatics/btx015).

Sequence database Version Count Count of proteins matching
any signature integrated signatures
UniProtKB2017_099060630579912988 (88.2%)73109013 (80.7%)
UniProtKB/TrEMBL2017_099005071179369067 (88.1%)72572286 (80.6%)
UniProtKB/Swiss-Prot2017_09555594543921 (97.9%)536727 (96.6%)

InterPro2GO

Total number of GO terms mapped to InterPro entries - 33419

List of InterPro2GO mappings. These are also available through the EBI GO browser QuickGO