Release notes

Latest release note

v.64
InterPro 64.0
6th July 2017

Features include:

  • The addition of 658 new InterPro entries.
  • An update to CDD (3.16).
  • Integration of 1259 new methods from the CDD (460), Pfam (436), SUPERFAMILY (4), PANTHER (146), CATH-Gene3D (19), PIRSF (17) and ProDom (177) databases.

Previous release notes

Contents and coverage of InterPro 64.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins.
InterPro release 64.0 contains 30876 entries (last entry: IPR035715), representing:

InterPro cites 53001 publications in PubMed.

Member database information

Signature database Version Signatures* Integrated signatures**
CATH-Gene3D 4.1.0 2737 1235
CDD 3.16 12805 2165
HAMAP 201701.18 2160 2160
PANTHER 11.1 91538 6224
Pfam 31.0 16712 16119
PIRSF 3.02 3285 3201
PRINTS 42.0 2106 1980
ProDom 2006.1 1894 1308
PROSITE patterns 20.132 1309 1289
PROSITE profiles 20.132 1174 1142
SFLD 2 480 146
SMART 7.1 1312 1264
SUPERFAMILY 1.75 2019 1479
TIGRFAMs 15.0 4488 4448

* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release
We use MobiDB-lite, a derivative of the MobiDB database, to provide consensus annotation of long-range intrinsic disorder in protein sequences. Read more about MobiDB-lite in Bioinformatics, 33(9), 2017, 1402–1404, (doi: 10.1093/bioinformatics/btx015).

Sequence database Version Count Count of proteins matching
any signature integrated signatures
UniProtKB2017_078858802678121677 (88.2%)71380569 (80.6%)
UniProtKB/TrEMBL2017_078803292677578215 (88.1%)70844347 (80.5%)
UniProtKB/Swiss-Prot2017_07555100543462 (97.9%)536222 (96.6%)

InterPro2GO

Total number of GO terms mapped to InterPro entries - 32484

List of InterPro2GO mappings. These are also available through the EBI GO browser QuickGO