Release 29.0, 20th October 2010
New features include:
- This release includes an update to PROSITE patterns and profiles (20.66), Gene3D (3.3.0), PIRSF (2.73), SUPERFAMILY (1.73) and SMART (6.1) and the integration of 731 new methods from the HAMAP, Gene3D, PIRSF, SUPERFAMILY and SMART databases.
- Please Note: Pfam release 24.0 matches were calculated using HMMER3. The majority of the updated signatures were stable; however some had significant increases or decreases in the numbers of proteins they matched (+/- 30% change), which changed the taxonomy and/or biology based on protein matches. We are reviewing these entries, checking that the InterPro entry annotation is still valid and reflects the taxonomy and biology of the proteins matched by the Pfam signatures. Those Pfam signatures which have not yet been through this review process were therefore temporarily removed from InterPro and will be re-integrated into the InterPro database during 2010. If you have any questions about this, please contact us via support.
Contents and coverage of InterPro 29.0
InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins. InterPro release 29.0 contains 21123 entries, representing:
Last entry: IPR023210
32445 publications in PUBMED are referenced from InterPro.
Member database information
|Signature Database||Version||Signatures*||Integrated Signatures**|
* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release.
|Sequence Database||Version||Count||count of proteins matching|
|any signature||integrated signatures|
|UniProtKB||2010_11||12869322||11029188 (85.7%)||10223817 (79.4%)|
|UniProtKB/TrEMBL||2010_11||12347303||10522000 (85.2%)||9725938 (78.8%)|
|UniProtKB/Swiss-Prot||2010_11||522019||507188 (97.2%)||497879 (95.4%)|