Release 22.0, 28 July 2009

New features include:

  • HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) as a new member database.
  • 18843 entries with 280 new methods from HAMAP and 135 from PRODOM.

Contents and coverage of InterPro 22.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins. InterPro release 22.0 contains 18843 entries, representing:

Active site 79
Binding site 52
Conserved site 506
Domain 5428
Family 11379
Region 1123
PTM 23
Repeat 253

Last entry: IPR020604

28072 publications in PUBMED are referenced from InterPro.

Member database information

Signature Database Version Signatures* Integrated Signatures**
HAMAP 280509 1633 280
PANTHER 6.1 30127 2135
Pfam 23.0 10340 10336
PIRSF 2.70 3212 2691
PRINTS 39.0 1950 1928
ProDom 2006.1 1894 834
PROSITE patterns 20.35 1316 1315
PROSITE profiles 20.35 801 779
SMART 5.1 724 720
TIGRFAMs 8.0 3603 3581
GENE3D 3.0.0 2147 1024
SUPERFAMILY 1.69 1538 1090

* Some signatures may not have matches to UniProtKB proteins.

** Not all signatures of a member database may be integrated at the time of an InterPro release.

Sequence Database Version Count count of proteins matching
any signature integrated signatures
UniProtKB 15.6 9421896 7516859 (79.8%) 7187599 (76.3%)
UniProt/Swiss-Prot 57.6 495880 478493 (96.5%) 469205 (94.6%)
UniProt/TrEMBL 40.6 8926016 7038366 (78.9%) 6718394 (75.3%)

InterPro to GO