Release 16.1, Monday October 8th 2007

InterPro 16.1 features include:

Contents and coverage of InterPro 16.1

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtkB proteins. InterPro release 16.1 contains 14768 entries, representing:

Active site 34
Binding site 22
Domain 4731
Family 9729
PTM 18
Repeat 234

Last entry: IPR016008

24520 publications in PUBMED are referenced from InterPro.

Member database information

Signature Database Version All Signatures Integrated Signatures
PANTHER 6.1 26313 2072
Pfam 21.0 8957 8957
PIRSF 2.70 2877 1034
PRINTS 38.0 1900 1898
ProDom 2005.1 3538 1054
PROSITE patterns 20.0 1331 1331
PROSITE profiles 20.0 675 654
SMART 5.1 724 721
TIGRFAMs 6.0 2949 2933
GENE3D 3.0.0 2147 837
SUPERFAMILY 1.69 1538 692

Sequence database statistics

Sequence Database Version Count Count of proteins matching
All Signatures Integrated Signatures
UniProtKB 12.2 5148042 4134012 (80.3%) 3909022 (75.9%)
UniProt/Swiss-Prot 54.2 283454 270090 (95.3%) 260723 (92.0%)
UniProt/TrEMBL 37.2 4864588 3863922 (79.4%) 3648299 (75.0%)

InterPro to GO

Forthcoming changes

Feedback

We need your help and would welcome any feedback. If you find errors or omissions please let us know. You can contact us at: EBI Support.

Acknowledgements

R.Apweiler (1), T.K.Attwood (4), A.Bairoch (2), A.Bateman (5), D.Binns (1), P.Bork (8), P.Bucher (3), L.Cerutti (3), R.Copley (13), E.Courcelle (6), U.Das (1), L.Daugherty (1), M.Dibley (7), R.Finn (5), J.Gough (11), D.Haft (9), N.Hulo (2), S.Hunter (1), D.Kahn (6), A.Kanapin (1), A. Kejariwal (14), D.Lonsdale (1), R.Lopez (1), I.Letunic (8), M.Madera (12), J.Maslen (1), C.McAnulla (1), J.McDowall (1), J.Mistry (5), A.Mitchell (1,4), N.Mulder (1), A.N.Nikolskaya (10), S.Orchard (1), C.Orengo (7), M.Pagni (3), C.Sigrist (2), P.D.Thomas (14), D.Wilson (12), C.H.Wu (10), C.Yates (7).

(1) EMBL Outstation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK;
(2) Swiss Institute for Bioinformatics, Geneva, Switzerland;
(3) Swiss Institute for Experimental Cancer Research, Lausanne, Switzerland;
(4) School of Biological Sciences, The University of Manchester, Manchester, UK;
(5) The Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK;
(6) CNRS/INRA, PRABI, 69622 Villeurbanne Cedex, France;
(7) Biochemistry and Molecular Biology Department, University College London, University of London, UK;
(8) Biocomputing Unit, EMBL-Heidelberg, Germany;
(9) The Institute for Genomic Research, Maryland, USA;
(10) Protein Information Resource, Georgetown University Medical Center, Washington, D.C., USA;
(11) Unite de Bioinformatique Structurale, Institut Pasteur, Paris, France;
(12) MRC Laboratory of Molecular Biology, Cambridge, UK;
(13) Wellcome Trust Centre for Human Genetics, Oxford, UK;
(14) Computational Biology, SRI International, 333 Ravenswood Ave., Menlo Park, CA 94025, USA.

Copyright

InterPro - Integrated Resource Of Protein Domains And Functional Sites. Copyright (C) 2001 The InterPro Consortium. This manual and the accompanying database may be copied and redistributed freely, without advance permission, provided that this Copyright statement is reproduced with each copy.