Release notes

Latest release note

v.69
InterPro 69.0
21st June 2018

Features include:

  • The addition of 411 new InterPro entries.
  • An update to MobiDB Lite (1.5).
  • Integration of 528 new methods from the CATH-Gene3D (3), CDD (78), PANTHER (436), Pfam (6), ProDom (3), SFLD (1) and SUPERFAMILY (1) databases.

Previous release notes

Contents and coverage of InterPro 69.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins.
InterPro release 69.0 contains 34358 entries (last entry: IPR039418), representing:

InterPro cites 56100 publications in PubMed.

Member database information

Signature database Version Signatures* Integrated signatures**
CATH-Gene3D 4.2.0 6119 2143
CDD 3.16 12805 2868
HAMAP 2018_03 2246 2244
PANTHER 12.0 90742 8297
Pfam 31.0 16712 16119
PIRSF 3.02 3285 3223
PRINTS 42.0 2106 1968
ProDom 2006.1 1894 1310
PROSITE patterns 2018_02 1309 1287
PROSITE profiles 2018_02 1210 1176
SFLD 3 303 147
SMART 7.1 1312 1263
SUPERFAMILY 1.75 2019 1602
TIGRFAMs 15.0 4488 4445

* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release
We use MobiDB-lite, a derivative of the MobiDB database, to provide consensus annotation of long-range intrinsic disorder in protein sequences. Read more about MobiDB-lite in Bioinformatics, 33(9), 2017, 1402-1404, (doi: 10.1093/bioinformatics/btx015).

Sequence database Version Count Count of proteins matching
any signature integrated signatures
UniProtKB2018_06116587823102218480 (87.7%)94041609 (80.7%)
UniProtKB/TrEMBL2018_06116030110101672839 (87.6%)93502581 (80.6%)
UniProtKB/Swiss-Prot2018_06557713545641 (97.8%)539028 (96.6%)

InterPro2GO

Total number of GO terms mapped to InterPro entries - 34302

List of InterPro2GO mappings. These are also available through the EBI GO browser QuickGO