Release notes

Latest release note

v.68
InterPro 68.0
26th April 2018

Features include:

  • The addition of 240 InterPro entries.
  • An update to HAMAP (2018_03), PROSITE patterns (2018_02) and PROSITE profiles (2018_02).
  • Integration of 381 new methods from the CATH-Gene3D (2), CDD (17), HAMAP (29), PANTHER (298), Pfam (16), ProDom (1), PROSITE profiles (16) and SUPERFAMILY (2) databases.

Previous release notes

Contents and coverage of InterPro 68.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins.
InterPro release 68.0 contains 33947 entries (last entry: IPR039010), representing:

InterPro cites 55370 publications in PubMed.

Member database information

Signature database Version Signatures* Integrated signatures**
CATH-Gene3D 4.2.0 6119 2140
CDD 3.16 12805 2790
HAMAP 2018_03 2246 2244
PANTHER 12.0 90742 7868
Pfam 31.0 16712 16114
PIRSF 3.02 3285 3223
PRINTS 42.0 2106 1968
ProDom 2006.1 1894 1307
PROSITE patterns 2018_02 1309 1288
PROSITE profiles 2018_02 1210 1176
SFLD 3 303 147
SMART 7.1 1312 1263
SUPERFAMILY 1.75 2019 1601
TIGRFAMs 15.0 4488 4445

* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release
We use MobiDB-lite, a derivative of the MobiDB database, to provide consensus annotation of long-range intrinsic disorder in protein sequences. Read more about MobiDB-lite in Bioinformatics, 33(9), 2017, 1402–1404, (doi: 10.1093/bioinformatics/btx015).

Sequence database Version Count Count of proteins matching
any signature integrated signatures
UniProtKB2018_04115316915101076817 (87.7%)93075570 (80.7%)
UniProtKB/TrEMBL2018_04114759640100531651 (87.6%)92537241 (80.6%)
UniProtKB/Swiss-Prot2018_04557275545166 (97.8%)538329 (96.6%)

InterPro2GO

Total number of GO terms mapped to InterPro entries - 33944

List of InterPro2GO mappings. These are also available through the EBI GO browser QuickGO