Histone-lysine N-methyltransferase, H3 lysine-79 specific (Q8TEK3)

Accession
Q8TEK3 (DOT1L_HUMAN)
Species
Homo sapiens (Human)
Length
1,537 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 200 400 600 800 1000 1200 1400 1537

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1537

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Other features

Residue annotation

  1. S-adenosylmethioni...

GO term prediction

Biological Process

GO:0006342 chromatin silencing
GO:0034729 histone H3-K79 methylation
GO:0051726 regulation of cell cycle

Molecular Function

GO:0018024 histone-lysine N-methyltransferase activity
GO:0031151 histone methyltransferase activity (H3-K79 specific)

Cellular Component

GO:0005634 nucleus