Werner syndrome ATP-dependent helicase (Q14191)

Accession
Q14191 (WRN_HUMAN)
Species
Homo sapiens (Human)
Length
1,432 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 200 400 600 800 1000 1200 1432

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1432

Detailed signature matches

Residue annotation

  1. catalytic site cd0...
  2. putative active si...
  3. putative substrate...
  4. ATP binding site c...
  5. putative Mg++ bind...
  6. nucleotide binding...
  7. ATP-binding site c...

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0044237 cellular metabolic process

Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0008408 3'-5' exonuclease activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity

Cellular Component

GO:0005622 intracellular