TNF receptor-associated factor 2 (Q12933)

Accession
Q12933 (TRAF2_HUMAN)
Species
Homo sapiens (Human)
Length
501 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 50 100 150 200 250 300 350 400 450 501

Domains and repeats

1 50 100 150 200 250 300 350 400 450 501

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. Zn binding site cd...
  2. trimer interface c...
  3. TNFR binding site ...
  4. TRADD binding site...

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042981 regulation of apoptotic process
GO:0046328 regulation of JNK cascade
GO:0051865 protein autoubiquitination

Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding

Cellular Component

None predicted.