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Ribose-phosphate pyrophosphokinase 1 (P60891)

Accession
P60891 (PRPS1_HUMAN)
Species
Homo sapiens (Human)
Length
318 amino acids (complete)
Source: UniProtKB

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 50 100 150 200 250 318

Domains and repeats

  1. Domain
1 50 100 150 200 250 318

Detailed signature matches

  1. Homologous superfamily IPR029057
    Phosphoribosyltransferase-like
    1. SSF53271
  2. Family IPR005946
    Ribose-phosphate pyrophosphokinase
    1. TIGR01251 (ribP_PPkin)
    2. PF14572 (Pribosyl_s...)
    3. PTHR10210
  3. Family IPR037515
    Ribose-phosphate pyrophosphokinase, bacterial-type
    1. MF_00583_B (RibP_PP...)
  4. Domain IPR029099
    Ribose-phosphate pyrophosphokinase, N-terminal domain
    1. PF13793 (Pribosyltr...)
  5. Domain IPR000836
    Phosphoribosyltransferase domain
    1. cd06223 (PRTases_typeI)
  6. SITE IPR000842
    Phosphoribosyl pyrophosphate synthetase, conserved site
    1. PS00114 (PRPP_SYNTHASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PTHR10210:SF60
  3. SM01400 (Pribosyltr...)

Residue annotation

  1. active site cd06223

GO term prediction

Biological Process

GO:0009116 nucleoside metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0044249 cellular biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity

Cellular Component

None predicted.