Tyrosine-protein kinase JAK3 (P52333)

Accession
P52333 (JAK3_HUMAN)
Species
Homo sapiens (Human)
Length
1,124 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 200 400 600 800 1000 1124

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1124

Detailed signature matches

Residue annotation

  1. phosphotyrosine bi...
  2. hydrophobic bindin...
  3. V617F mutation sit...
  4. ATP binding site c...
  5. active site cd05081
  6. polypeptide substr...
  7. activation loop (A...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0035556 intracellular signal transduction

Molecular Function

GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding

Cellular Component

GO:0005856 cytoskeleton
GO:0016020 membrane