Fatty acid synthase (P49327)

Accession
P49327 (FAS_HUMAN)
Species
Homo sapiens (Human)
Length
2,511 amino acids (complete)
Source: UniProtKB


Protein family membership

None predicted.

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 500 1000 1500 2000 2511

Domains and repeats

1 500 1000 1500 2000 2511

Detailed signature matches

    1. PF00109 (ketoacyl-synt)
    1. SM00825 (PKS_KS)
    1. PF02801 (Ketoacyl-s...)
    1. PF16197 (KAsynt_C_a...)
    1. PF00698 (Acyl_transf_1)
    1. SM00827 (PKS_AT)
    1. SM00826 (PKS_DH)
    2. PF14765 (PS-DH)
    1. PF08242 (Methyltran...)
    1. SM00829 (PKS_ER)
    1. PF00107 (ADH_zinc_N)
    1. PS50075 (CARRIER)
    2. PF00550 (PP-binding)
    1. SM00823 (PKS_PP)
    1. PF00975 (Thioesterase)
    1. PS00606 (B_KETOACYL...)
    1. PS00012 (PHOSPHOPAN...)

Residue annotation

  1. active site cd00833
  2. S-adenosylmethioni...
  3. NAD(P) binding sit...
  4. putative NADP bind...
  5. active site cd08954

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0004312 fatty acid synthase activity
GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0016297 acyl-[acyl-carrier-protein] hydrolase activity
GO:0016491 oxidoreductase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0031177 phosphopantetheine binding

Cellular Component

None predicted.