Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (P42336)

Accession
P42336 (PK3CA_HUMAN)
Species
Homo sapiens (Human)
Length
1,068 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 100 200 300 400 500 600 700 800 900 1000 1068

Domains and repeats

1 100 200 300 400 500 600 700 800 900 1000 1068

Detailed signature matches

Residue annotation

  1. p110alpha-p85alpha...
  2. ATP binding site c...
  3. Ras binding site c...
  4. catalytic loop cd0...
  5. activation loop (A...
  6. regulatory subunit...

GO term prediction

Biological Process

GO:0046854 phosphatidylinositol phosphorylation
GO:0048015 phosphatidylinositol-mediated signaling

Molecular Function

GO:0005488 binding
GO:0016301 kinase activity
GO:0016303 1-phosphatidylinositol-3-kinase activity

Cellular Component

None predicted.