CAD protein (P27708)

Accession
P27708 (PYR1_HUMAN)
Species
Homo sapiens (Human)
Length
2,225 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
  3. Homologous superfamily
1 500 1000 1500 2225

Domains and repeats

1 500 1000 1500 2225

Detailed signature matches

    1. MF_01209 (CPSase_S_...)
    2. TIGR01368 (CPSaseII...)
    1. TIGR01369 (CPSaseII...)
    1. PS00097 (CARBAMOYLT...)
    2. PR00100 (AOTCASE)
    1. TIGR00670 (asp_carb_tr)
    2. PR00101 (ATCASE)
    3. MF_00001 (Asp_carb_tr)
    1. PF00988 (CPSase_sm_...)
    2. SM01097 (CPSase_sm_...)
    1. PF00117 (GATase)
    2. PS51273 (GATASE_TYPE_1)
    1. cd01744 (GATase1_CP...)
    1. PS50975 (ATP_GRASP)
    1. PS00867 (CPSASE_2)
    2. PS00866 (CPSASE_1)
    3. PF02786 (CPSase_L_D2)
    1. SM01096 (CPSase_L_D3)
    2. PF02787 (CPSase_L_D3)
    1. PF01979 (Amidohydro_1)
    1. PF02729 (OTCace_N)
    1. PF00185 (OTCace)
    1. PS00483 (DIHYDROORO...)
    2. PS00482 (DIHYDROORO...)

Residue annotation

  1. catalytic site cd0...
  2. subunit interface ...
  3. probable substrate...
  4. active site cd01316

GO term prediction

Biological Process

GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006520 cellular amino acid metabolic process
GO:0006541 glutamine metabolic process
GO:0006807 nitrogen compound metabolic process

Molecular Function

GO:0004070 aspartate carbamoyltransferase activity
GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0046872 metal ion binding

Cellular Component

None predicted.