Adenomatous polyposis coli protein (P25054)

P25054 (APC_HUMAN)
Homo sapiens (Human)
2,843 amino acids (complete)
Source: UniProtKB

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 500 1000 1500 2000 2500 2843

Domains and repeats

1 500 1000 1500 2000 2500 2843

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Other features

GO term prediction

Biological Process

GO:0000281 mitotic cytokinesis
GO:0006974 cellular response to DNA damage stimulus
GO:0007026 negative regulation of microtubule depolymerization
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0016055 Wnt signaling pathway
GO:0016477 cell migration
GO:0030178 negative regulation of Wnt signaling pathway
GO:0043065 positive regulation of apoptotic process

Molecular Function

GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding

Cellular Component

GO:0005634 nucleus
GO:0005737 cytoplasm