Trifunctional purine biosynthetic protein adenosine-3 (P22102)

Accession
P22102 (PUR2_HUMAN)
Species
Homo sapiens (Human)
Length
1,010 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 100 200 300 400 500 600 700 800 900 1010

Domains and repeats

1 100 200 300 400 500 600 700 800 900 1010

Detailed signature matches

Residue annotation

  1. dimerization inter...
  2. putative ATP bindi...
  3. active site cd08645
  4. substrate binding ...
  5. cosubstrate bindin...
  6. catalytic site cd0...

GO term prediction

Biological Process

GO:0006189 'de novo' IMP biosynthetic process
GO:0009058 biosynthetic process
GO:0009113 purine nucleobase biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004637 phosphoribosylamine-glycine ligase activity
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004644 phosphoribosylglycinamide formyltransferase activity
GO:0005524 ATP binding
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
GO:0046872 metal ion binding

Cellular Component

GO:0005737 cytoplasm