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Arachidonate 12-lipoxygenase, 12S-type (P18054)

Accession
P18054 (LOX12_HUMAN)
Species
Homo sapiens (Human)
Length
663 amino acids (complete)
Source: UniProtKB

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 100 200 300 400 500 600 663

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 663

Detailed signature matches

  1. Homologous superfamily IPR036392
    PLAT/LH2 domain superfamily
    1. SSF49723
  2. Homologous superfamily IPR036226
    Lipoxigenase, C-terminal domain superfamily
    1. SSF48484
  3. Family IPR000907
    Lipoxygenase
    1. PTHR11771
  4. Family IPR001885
    Lipoxygenase, mammalian
    1. PR00467 (MAMLPOXGNASE)
  5. Domain IPR001024
    PLAT/LH2 domain
    1. SM00308 (LH2)
    2. PS50095 (PLAT)
    3. PF01477 (PLAT)
  6. Domain IPR013819
    Lipoxygenase, C-terminal
    1. PF00305 (Lipoxygenase)
    2. PR00087 (LIPOXYGENASE)
    3. PS51393 (LIPOXYGENA...)
  7. SITE IPR020833
    Lipoxygenase, iron binding site
    1. PS00711 (LIPOXYGENA...)
  8. SITE IPR020834
    Lipoxygenase, conserved site
    1. PS00081 (LIPOXYGENA...)

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding

Cellular Component

None predicted.