Cystic fibrosis transmembrane conductance regulator (P13569)

Accession
P13569 (CFTR_HUMAN)
Species
Homo sapiens (Human)
Length
1,480 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 200 400 600 800 1000 1200 1480

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 200 400 600 800 1000 1200 1480

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03291
  4. ABC transporter si...
  5. Walker B cd03291
  6. D-loop cd03291
  7. H-loop/switch regi...
  8. Walker A/P-loop cd...
  9. ATP binding site c...
  10. Q-loop/lid cd03289
  11. ABC transporter si...
  12. Walker B cd03289
  13. D-loop cd03289
  14. H-loop/switch regi...

GO term prediction

Biological Process

GO:0006811 ion transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005254 chloride channel activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane