DNA topoisomerase 1 (P11387)

Accession
P11387 (TOP1_HUMAN)
Species
Homo sapiens (Human)
Length
765 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 100 200 300 400 500 600 700 765

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 765

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. DNA binding cd03488
  2. topo1 poison bindi...
  3. DNA binding site c...
  4. active site cd00659

GO term prediction

Biological Process

GO:0006265 DNA topological change

Molecular Function

GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Cellular Component

GO:0005694 chromosome