Protein

Insulin-like growth factor 1 receptor (P08069)

Accession
P08069 (IGF1R_HUMAN)
Species
Homo sapiens (Human)
Length
1,367 amino acids (complete)
Source: UniProtKB


Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Repeat
1 200 400 600 800 1000 1200 1367

Detailed signature matches

Residue annotation

  1. Interdomain contac...
  2. Cytokine receptor ...
  3. Interdomain contac...
  4. Interdomain contac...
  5. Cytokine receptor ...
  6. ATP binding site c...
  7. active site cd05032
  8. polypeptide substr...
  9. activation loop (A...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0046777 protein autophosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043560 insulin receptor substrate binding

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane