Retinoblastoma-associated protein (P06400)

P06400 (RB_HUMAN)
Homo sapiens (Human)
928 amino acids (complete)
Source: UniProtKB

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 928

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00043 (CYCLIN)

GO term prediction

Biological Process

GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006915 apoptotic process
GO:0008285 negative regulation of cell proliferation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051726 regulation of cell cycle
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Molecular Function

GO:0008134 transcription factor binding

Cellular Component

GO:0005634 nucleus
GO:0035189 Rb-E2F complex