Insulin receptor (P06213)

Homo sapiens (Human)
1,382 amino acids (complete)
Source: UniProtKB

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Repeat
1 200 400 600 800 1000 1200 1382

Detailed signature matches

Residue annotation

  1. Interdomain contac...
  2. Interdomain contac...
  3. Cytokine receptor ...
  4. ATP binding site c...
  5. active site cd05061
  6. PTP1B noncatalytic...
  7. polypeptide substr...
  8. activation loop (A...
  9. APS (SH2 domain) i...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0046777 protein autophosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043560 insulin receptor substrate binding

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane