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Eukaryotic translation initiation factor 2 subunit 1 (P05198)

Accession
P05198 (IF2A_HUMAN)
Species
Homo sapiens (Human)
Length
315 amino acids (complete)
Source: UniProtKB

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 50 100 150 200 250 315

Domains and repeats

  1. Domain
1 50 100 150 200 250 315

Detailed signature matches

  1. Homologous superfamily IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249
  2. Homologous superfamily IPR024054
    Translation initiation factor 2, alpha subunit, middle domain superfamily
    1. G3DSA:1.10.15...
    2. SSF116742
  3. Homologous superfamily IPR024055
    Translation initiation factor 2, alpha subunit, C-terminal
    1. SSF110993
    2. G3DSA:3.30.70...
  4. Family IPR011488
    Translation initiation factor 2, alpha subunit
    1. PF07541 (EIF_2_alpha)
    2. PTHR10602
  5. Domain IPR022967
    RNA-binding domain, S1
    1. SM00316 (S1)
  6. Domain IPR003029
    S1 domain
    1. PS50126 (S1)
    2. PF00575 (S1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. cd04452 (S1_IF2_alpha)
  3. mobidb-lite (disord...)

Residue annotation

  1. kinase interaction...
  2. eIF2B interation s...
  3. protein synthesis ...

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity

Cellular Component

None predicted.