Protein

Structures: HLA class II histocompatibility antigen, DRB1-1 beta chain (P04229)

Accession
P04229 (2B11_HUMAN)
Species
Homo sapiens (Human)
Length
266 amino acids (complete)
Source: UniProtKB


Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 266

Structural features and predictions

  1. no IPR
    Structural features
    1. CATH
    2. PDB
    3. SCOP

Solved structures for this protein

ID Structure Description
4gbx Structure image for 4gbx Crystal structure of an immune complex at pH 6.5
1jws Structure image for 1jws Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1
1t5x Structure image for 1t5x HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2
1jwm Structure image for 1jwm Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3
1lo5 Structure image for 1lo5 Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II
1kg0 Structure image for 1kg0 Structure of the Epstein-Barr Virus gp42 Protein Bound to the MHC class II Receptor HLA-DR1
1seb Structure image for 1seb COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB
2g9h Structure image for 2g9h Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule
2xn9 Structure image for 2xn9 CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN HUMAN T CELL RECEPTOR, STAPHYLOCOCCAL ENTEROTOXIN H AND HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II
4aen Structure image for 4aen HLA-DR1 with covalently linked CLIP106-120 in reversed orientation
1dlh Structure image for 1dlh CRYSTAL STRUCTURE OF THE HUMAN CLASS II MHC PROTEIN HLA-DR1 COMPLEXED WITH AN INFLUENZA VIRUS PEPTIDE
1r5i Structure image for 1r5i Crystal structure of the MAM-MHC complex
4i5b Structure image for 4i5b Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
1fyt Structure image for 1fyt CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1
1klu Structure image for 1klu Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
4e41 Structure image for 4e41 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
4c56 Structure image for 4c56 X-ray structure of the complex between staphylococcal enterotoxin B, T cell receptor and major histocompatibility complex class II
2ipk Structure image for 2ipk Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2
2icw Structure image for 2icw Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule
3s4s Structure image for 3s4s Crystal structure of CD4 mutant bound to HLA-DR1
1hxy Structure image for 1hxy CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H IN COMPLEX WITH HUMAN MHC CLASS II
1sjh Structure image for 1sjh HLA-DR1 complexed with a 13 residue HIV capsid peptide
1t5w Structure image for 1t5w HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR)
2fse Structure image for 2fse Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen
2oje Structure image for 2oje Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA
3s5l Structure image for 3s5l Crystal structure of CD4 mutant bound to HLA-DR1
2ian Structure image for 2ian Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
3l6f Structure image for 3l6f Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1
3pgc Structure image for 3pgc Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation
3pgd Structure image for 3pgd Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation
4fqx Structure image for 4fqx Crystal structure of HLA-DM bound to HLA-DR1
1aqd Structure image for 1aqd HLA-DR1 (DRA, DRB1 0101) HUMAN CLASS II HISTOCOMPATIBILITY PROTEIN (EXTRACELLULAR DOMAIN) COMPLEXED WITH ENDOGENOUS PEPTIDE
1jwu Structure image for 1jwu Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2
1klg Structure image for 1klg Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
1pyw Structure image for 1pyw Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
3qxa Structure image for 3qxa HLA-DR1 bound with CLIP peptide
4ah2 Structure image for 4ah2 HLA-DR1 with covalently linked CLIP106-120 in canonical orientation
4ov5 Structure image for 4ov5 Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket
1sje Structure image for 1sje HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation
2iam Structure image for 2iam Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
3qxd Structure image for 3qxd F54C HLA-DR1 bound with CLIP peptide
3pdo Structure image for 3pdo Crystal Structure of HLA-DR1 with CLIP102-120