3-hydroxy-3-methylglutaryl-coenzyme A reductase (P04035)

Accession
P04035 (HMDH_HUMAN)
Species
Homo sapiens (Human)
Length
888 amino acids (complete)
Source: UniProtKB


Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
  3. Homologous superfamily
1 100 200 300 400 500 600 700 800 888

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 888

Detailed signature matches

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process
GO:0015936 coenzyme A metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0050662 coenzyme binding

Cellular Component

GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane